The role of non‐coding RNAs in drug resistance of oral squamous cell carcinoma and therapeutic potential

X Meng, QY Lou, WY Yang, YR Wang… - Cancer …, 2021 - Wiley Online Library
Oral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises
from the interaction of multiple factors including tobacco, alcohol consumption, and betel …

Saponins in cancer treatment: Current progress and future prospects

OO Elekofehinti, O Iwaloye, F Olawale, EO Ariyo - Pathophysiology, 2021 - mdpi.com
Saponins are steroidal or triterpenoid glycoside that is distinguished by the soap-forming
nature. Different saponins have been characterized and purified and are gaining attention in …

New visions on natural products and cancer therapy: autophagy and related regulatory pathways

A Martelli, M Omrani, M Zarghooni, V Citi, S Brogi… - Cancers, 2022 - mdpi.com
Simple Summary In the past few years, clinical as well as regular scientists have been
paying attention to medicinal applications of natural products. There are several …

The multifaceted functions of autophagy in breast cancer development and treatment

NJ Niklaus, I Tokarchuk, M Zbinden, AM Schläfli… - Cells, 2021 - mdpi.com
Macroautophagy (herein referred to as autophagy) is a complex catabolic process
characterized by the formation of double-membrane vesicles called autophagosomes …

Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response

M Ashrafizadeh, MDA Paskeh, S Mirzaei… - Journal of Experimental …, 2022 - Springer
Prostate cancer is a leading cause of death worldwide and new estimates revealed prostate
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …

Helicobacter pylori promotes gastric cancer progression through the tumor microenvironment

L Zhu, Y Huang, H Li, S Shao - Applied Microbiology and Biotechnology, 2022 - Springer
Gastric cancer (GC) is a leading type of cancer. Although immunotherapy has yielded
important recent progress in the treatment of GC, the prognosis remains poor due to drug …

The comprehensive analysis identified an autophagy signature for the prognosis and the immunotherapy efficiency prediction in lung adenocarcinoma

X Li, Z Dai, X Wu, N Zhang, H Zhang, Z Wang… - Frontiers in …, 2022 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is a fatal malignancy in the world. Growing
evidence demonstrated that autophagy-related genes regulated the immune cell infiltration …

Ultrasound-targeted microbubble destruction: modulation in the tumor microenvironment and application in tumor immunotherapy

Y Han, J Sun, H Wei, J Hao, W Liu, X Wang - Frontiers in immunology, 2022 - frontiersin.org
Tumor immunotherapy has shown strong therapeutic potential for stimulating or
reconstructing the immune system to control and kill tumor cells. It is a promising and …

Autophagy regulators in cancer

J Zhang, Q Xiang, M Wu, YZ Lao, YF Xian… - International Journal of …, 2023 - mdpi.com
Autophagy plays a complex impact role in tumor initiation and development. It serves as a
double-edged sword by supporting cell survival in certain situations while also triggering …

The Prognosis of Cancer Depends on the Interplay of Autophagy, Apoptosis, and Anoikis within the Tumor Microenvironment

S Gulia, P Chandra, A Das - Cell Biochemistry and Biophysics, 2023 - Springer
Within the tumor microenvironment, the fight between the immune system and cancer
influences tumor transformation. Metastasis formation is an important stage in the …