Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders

MA Katzman, P Bleau, P Blier, P Chokka, K Kjernisted… - BMC psychiatry, 2014 - Springer
Background Anxiety and related disorders are among the most common mental disorders,
with lifetime prevalence reportedly as high as 31%. Unfortunately, anxiety disorders are …

Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders

AC Campos, FA Moreira, FV Gomes… - … of the Royal …, 2012 - royalsocietypublishing.org
Cannabidiol (CBD) is a major phytocannabinoid present in the Cannabis sativa plant. It
lacks the psychotomimetic and other psychotropic effects that the main plant compound Δ 9 …

[PDF][PDF] Practice guideline for the treatment of patients with obsessive-compulsive disorder

American Psychiatric Association, LM Koran… - 2007 - academia.edu
PRACTICE GUIDELINE FOR THE TREATMENT OF PATIENTS WITH OBSESSIVE-COMPULSIVE
DISORDER Page 1 Not for Distribution or Citation Draft 2, December 6, 2005 PRACTICE …

Glutamate abnormalities in obsessive compulsive disorder: neurobiology, pathophysiology, and treatment

C Pittenger, MH Bloch, K Williams - Pharmacology & therapeutics, 2011 - Elsevier
Obsessive compulsive disorder is prevalent, disabling, incompletely understood, and often
resistant to current therapies. Established treatments consist of specialized cognitive …

Randomized controlled crossover trial of ketamine in obsessive-compulsive disorder: proof-of-concept

CI Rodriguez, LS Kegeles, A Levinson… - …, 2013 - nature.com
Serotonin reuptake inhibitors (SRIs), the first-line pharmacological treatment for obsessive-
compulsive disorder (OCD), have two limitations: incomplete symptom relief and 2–3 months …

[HTML][HTML] Clinical advances in obsessive-compulsive disorder: a position statement by the International College of Obsessive-Compulsive Spectrum Disorders

NA Fineberg, E Hollander, S Pallanti… - International clinical …, 2020 - journals.lww.com
In this position statement, developed by The International College of Obsessive-Compulsive
Spectrum Disorders, a group of international experts responds to recent developments in the …

[HTML][HTML] Treatment-resistant OCD: Pharmacotherapies in adults

PJ Van Roessel, G Grassi, EN Aboujaoude… - Comprehensive …, 2023 - Elsevier
Serotonin reuptake inhibitor (SRI) medications are well established as first-line
pharmacotherapeutic treatment for Obsessive-Compulsive Disorder (OCD). However …

The role of glutamate signaling in the pathogenesis and treatment of obsessive–compulsive disorder

K Wu, GL Hanna, DR Rosenberg, PD Arnold - … Biochemistry and Behavior, 2012 - Elsevier
Obsessive–compulsive disorder (OCD) is a common and often debilitating neuropsychiatric
condition characterized by persistent intrusive thoughts (obsessions), repetitive ritualistic …

New perspectives in glutamate and anxiety

CR Bermudo-Soriano, MM Perez-Rodriguez… - Pharmacology …, 2012 - Elsevier
Anxiety and stress-related disorders, namely posttraumatic stress disorder (PTSD),
generalized anxiety disorder (GAD), obsessive–compulsive disorder (ODC), social and …

Memantine add-on in moderate to severe obsessive-compulsive disorder: randomized double-blind placebo-controlled study

A Ghaleiha, N Entezari, A Modabbernia… - Journal of psychiatric …, 2013 - Elsevier
There is a growing body of evidence for the efficacy of memantine augmentation in patients
with obsessive-compulsive disorder (OCD). However, to date, no double-blind study has …