Introduction: BRAF mutant colorectal cancer (BRAF MT CRC) is a unique category of
colorectal tumour with peculiar molecular, pathological and clinical features and poor …

This study aimed to estimate the incidence of KRAS, NRAS, and BRAF mutations in the
Moroccan population, and investigate the associations of KRAS and NRAS gene mutations …

Colorectal cancer (CRC) is a highly lethal disease worldwide. The majority of patients
receiving targeted therapy or chemotherapy develop drug resistance, while its molecular …

Background Evaluating the tumor RAS/BRAF status is important for treatment selection and
prognosis assessment in metastatic colorectal cancer (mCRC) patients. Correction of …

Background Osimertinib belongs to the third-generation epidermal growth factor receptor
tyrosine kinase inhibitor that has shown positive effects in treating lung adenocarcinoma …

Background: Colorectal cancer is one of the most common types of cancer and the cause of
death of a large number of patients and requires investigating the causes of the disease and …

Colorectal cancer is one of the most common malignant tumors worldwide, responsible for
the second and fourth highest mortality among men and women, respectively(1, 2). Standard …

سابقه و هدف: سرطان کولورکتال یکی از شایعترین انواع سرطان و علت مرگ و میر تعداد بالایی از
بیماران است و نیاز به بررسی علل ایجاد بیماری و اتخاذ روش های هدفمند درمانی دارد. با توجه به …‎

This study investigated the molecular mechanisms that could predict the efficacy of
Epidermal Growth Factor Receptor (EGFR) targeted therapy in Indian colorectal cancer …

There are three main treatment methods for locally advanced stage II–III rectal cancer
patients: surgery using the total mesorectal (TME) technique, radiation therapy (RT) and 5 …