Application of isothermal titration calorimetry as a tool to study natural product interactions
O Callies, AH Daranas - Natural product reports, 2016 - pubs.rsc.org
Covering: up to February 2015 Over the past twenty-five years, isothermal titration
calorimetry (ITC) has become a potent tool for the study a great variety of molecular …
calorimetry (ITC) has become a potent tool for the study a great variety of molecular …
[HTML][HTML] Molecular spectroscopic markers of DNA damage
K Sofińska, N Wilkosz, M Szymoński, E Lipiec - Molecules, 2020 - mdpi.com
Every cell in a living organism is constantly exposed to physical and chemical factors which
damage the molecular structure of proteins, lipids, and nucleic acids. Cellular DNA lesions …
damage the molecular structure of proteins, lipids, and nucleic acids. Cellular DNA lesions …
[HTML][HTML] Cytotoxic effects of 5-azacytidine on primary tumour cells and cancer stem cells from oral squamous cell carcinoma: An in vitro FTIRM analysis
V Notarstefano, A Belloni, S Sabbatini, C Pro, G Orilisi… - Cells, 2021 - mdpi.com
In the present study, the cytotoxic effects of 5-azacytidine on primary Oral Squamous Cell
Carcinoma cells (OSCCs) from human biopsies, and on Cancer Stem Cells (CSCs) from the …
Carcinoma cells (OSCCs) from human biopsies, and on Cancer Stem Cells (CSCs) from the …
Exploiting fourier transform infrared and Raman microspectroscopies on cancer stem cells from oral squamous cells carcinoma: New evidence of acquired cisplatin …
V Notarstefano, S Sabbatini, C Pro, A Belloni, G Orilisi… - Analyst, 2020 - pubs.rsc.org
Oral Squamous Cells Carcinoma (OSCC) is characterised by the risk of recurrence and the
onset of a refractoriness response to chemotherapy drugs. These phenomena have been …
onset of a refractoriness response to chemotherapy drugs. These phenomena have been …
Determination of Curcumin on Functionalized Carbon Nano Tube Modified Electrode and Probing its Interaction with DNA and Copper Ion
S Sahoo, AK Satpati - Journal of Analysis and Testing, 2023 - Springer
Voltammetry measurements have been employed to investigate the redox behaviour of
curcumin in aqueous media using functionalized carbon nanotube (FCNTs) modified glassy …
curcumin in aqueous media using functionalized carbon nanotube (FCNTs) modified glassy …
Prospecting the cancer therapeutic edge of chitosan-based gold nanoparticles through conformation selective binding to the parallel G-quadruplex formed by short …
The biological relevance of G4 structures formed in telomere & oncogenes promoters make
them extremely crucial therapeutic target for cancer treatment. Herein, we have synthesized …
them extremely crucial therapeutic target for cancer treatment. Herein, we have synthesized …
A vibrational in vitro approach to evaluate the potential of monoolein nanoparticles as isofuranodiene carrier in MDA-MB 231 breast cancer cell line: New insights from …
V Notarstefano, M Pisani, M Bramucci… - … Acta Part A: Molecular …, 2022 - Elsevier
Isofuranodiene (IFD) is a sesquiterpene occurring in several plant species, which proved to
have multiple anticancer activities. IFD has a lipophilic nature and, hence, a very low water …
have multiple anticancer activities. IFD has a lipophilic nature and, hence, a very low water …
[HTML][HTML] Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques
JL Denbigh, D Perez-Guaita, RR Vernooij, MJ Tobin… - Scientific Reports, 2017 - nature.com
Acute myeloid leukaemia (AML) is a life threatening cancer for which there is an urgent
clinical need for novel therapeutic approaches. A redeployed drug combination of …
clinical need for novel therapeutic approaches. A redeployed drug combination of …
The effects of paclitaxel in the combination of diamond nanoparticles on the structure of human serum albumin (HSA) and their antiproliferative role on MDA-MB …
A Hekmat, F Salavati, S Hesami Tackallou - The Protein Journal, 2020 - Springer
Since the interactions of anti-cancer agents with blood constituents, in particular with human
serum albumin (HSA) may have a major impact on drug pharmacology, the present study …
serum albumin (HSA) may have a major impact on drug pharmacology, the present study …
Binding studies of guggulsterone-E to calf thymus DNA by multi-spectroscopic, calorimetric and molecular docking studies
Guggulsterone, a sterol found in plants is used as an ayurvedic medicine for many diseases
such as obesity, internal tumors, ulcers etc. E and Z are two isoforms of guggulsterone …
such as obesity, internal tumors, ulcers etc. E and Z are two isoforms of guggulsterone …