Overweight and obesity have reached pandemic levels on a worldwide basis and are
associated with increased risk and worse prognosis for many but not all malignancies …

Background Preclinical and clinical translational research supports the role of an ω-3 fatty
acid diet for prostate cancer prevention and treatment. The anti-prostate cancer effects of an …

Background The antiprostate cancer effects of dietary ω-3 fatty acids (FAs) were previously
found to be dependent on host G-protein coupled receptor 120 (GPR120). Using an …

BACKGROUND Preclinical and clinical studies suggest that a fish oil‐based diet may play a
role in delaying the progression of prostate cancer through a number of different …

Background Several lines of evidence suggest effects of dietary fat on prostate cancer (PCa)
development and progression. Targeting omega (ω)‐3: ω6 fatty acids (FA) ratio could be …

Background. We aimed to examine whether proinflammatory cytokines participated in
prostate cancer (PCa) development and progression promoted by high‐fat diet (HFD) …

Background GPR120, a G protein–coupled receptor for long-chain polyunsaturated fatty
acids (FAs), mediates the anti-inflammatory effects of omega-3 (ω-3) FAs. We investigated …

Background In vitro studies evidenced antitumor effects of omega‐3 polyunsaturated fatty
acids ([n− 3] PUFAs), but their effects on prostate cancer (PCa) remain controversial in …

Epigenetics/epigenomics has been shown to be involved in carcinogenesis. However, how
the epigenome would be altered in the transgenic adenocarcinoma of the mouse prostate …

Purpose We aimed to examine the effect of high-fat diet (HFD) on prostate cancer (PCa)
development and progression and to investigate whether metformin would postpone PCa …