Parasite infection, carcinogenesis and human malignancy

H Van Tong, PJ Brindley, CG Meyer, TP Velavan - EBioMedicine, 2017 - thelancet.com
Cancer may be induced by many environmental and physiological conditions. Infections
with viruses, bacteria and parasites have been recognized for years to be associated with …

Liver fluke-associated biliary tract cancer

P Prueksapanich, P Piyachaturawat… - Gut and …, 2017 - pmc.ncbi.nlm.nih.gov
Cholangiocarcinoma (CCA) is an aggressive cancer arising from epithelial cells of the bile
duct. Most patients with CCA have an unresectable tumor at the time of diagnosis. In …

The liver fluke Opisthorchis felineus: biology, epidemiology and carcinogenic potential

MY Pakharukova, VA Mordvinov - Transactions of the Royal …, 2016 - academic.oup.com
The liver fluke Opisthorchis felineus is a member of the triad of epidemiologically important
liver fluke species belonging to the family Opisthorchiidae and the major agent causing …

Why does infection with some helminths cause cancer?

PJ Brindley, JMC Da Costa, B Sripa - Trends in cancer, 2015 - cell.com
Infections with Opisthorchis viverrini, Clonorchis sinensis, and Schistosoma haematobium
are classified as group 1 biological carcinogens: definitive causes of cancer. These worms …

Update on pathogenesis of opisthorchiasis and cholangiocarcinoma

B Sripa, S Tangkawattana, PJ Brindley - Advances in parasitology, 2018 - Elsevier
Infection with the food-borne liver fluke Opisthorchis viverrini causes cholangiocarcinoma
(CCA). Whereas the cause of CCA in the West remains obscure, the principal risk factor in …

Liver fluke infection and cholangiocarcinoma: a review

S Zheng, Y Zhu, Z Zhao, Z Wu, K Okanurak, Z Lv - Parasitology research, 2017 - Springer
Parasites are significant groups for carcinogenesis among which liver flukes, including
Opisthorchis viverrini and Clonorchis sinensis, are typical representatives causing …

Dysregulated microRNA expression profiles in cholangiocarcinoma cell-derived exosomes

S Kitdumrongthum, C Metheetrairut, V Charoensawan… - Life sciences, 2018 - Elsevier
Aim Cholangiocarcinoma (CCA) is a malignant tumor of bile duct epithelial cells. The
prognosis of CCA is poor due to lack of effective therapeutic targets and detection at an …

Helminth infection–induced malignancy

PJ Brindley, A Loukas - PLoS pathogens, 2017 - journals.plos.org
Infectious diseases cause more than 20% of cancers in the developing world [1]. About a
dozen pathogens including Epstein-Barr virus and human T cell lymphocytotropic virus 1 are …

From the discovery of helminths to the discovery of their carcinogenic potential

S Jain, M Rana - Parasitology Research, 2024 - Springer
Cancer involves a major aberration in the normal behaviour of cells, making them divide
continuously, which interferes with the normal physiology of the body. The link between …

Identification of potential inhibitors of Fasciola gigantica thioredoxin1: computational screening, molecular dynamics simulation, and binding free energy studies

R Shukla, H Shukla, P Kalita, A Sonkar… - Journal of …, 2018 - Taylor & Francis
Fasciola gigantica is the causative organism of fascioliasis and is responsible for major
economic losses in livestock production globally. F. gigantica thioredoxin1 (FgTrx1) is an …