Caspase-9: a multimodal therapeutic target with diverse cellular expression in human disease
MI Avrutsky, CM Troy - Frontiers in pharmacology, 2021 - frontiersin.org
Caspase-9, a cysteine-aspartic protease known for its role as an initiator of intrinsic
apoptosis, regulates physiological cell death and pathological tissue degeneration. Its …
apoptosis, regulates physiological cell death and pathological tissue degeneration. Its …
Celecoxib activates autophagy by inhibiting the mTOR signaling pathway and prevents apoptosis in nucleus pulposus cells
W Chen, M Yasen, H Wang, C Zhuang, Z Wang… - BMC Pharmacology and …, 2022 - Springer
Background Intervertebral disc degeneration results from a variety of etiologies, including
inflammation and aging. Degenerated intervertebral discs feature down-regulated …
inflammation and aging. Degenerated intervertebral discs feature down-regulated …
The Relationship Between Inflammatory Processes and Apoptosis in Lumbar Disc Degeneration
Objective Degenerative Disc Disease (DDD) is a common health problem in the population.
There are recent studies focusing on relationship between DDD and immunological factors …
There are recent studies focusing on relationship between DDD and immunological factors …
The Identification of Human Translational Biomarkers of Neuropathic Pain and Cross-Species Validation Using an Animal Model
B Young, J Stephenson, B Islam, NN Burke… - Molecular …, 2023 - Springer
Neuropathic pain is a common chronic condition, which remains poorly understood. Many
patients receiving treatment continue to experience severe pain, due to limited …
patients receiving treatment continue to experience severe pain, due to limited …
[PDF][PDF] Prophylactic Effects of Losartan in Intestinal Ischemia-Reperfusion Injury Model
S Beskisiz - Analytical and Quantitative Cytopathology and …, 2021 - academia.edu
OBJECTIVE: To investigate the protective effect of losartan, an angiotensin II type 1 receptor
blocker with antioxidative effect on intestinal ischemia-reperfusion (I/R) injury in rats, against …
blocker with antioxidative effect on intestinal ischemia-reperfusion (I/R) injury in rats, against …