Cancer stem cells (CSCs) are a subpopulation of cells that can initiate, self-renew, and
sustain tumor growth. CSCs are responsible for tumor metastasis, recurrence, and drug …

Tumor cells and corrupt stromal cells in the tumor microenvironment usually overexpress
cancer-specific markers that are absent or barely detectable in normal cells, providing …

By following simple protein engineering steps, recombinant proteins with promising
applications in the field of drug delivery can be assembled in the form of functional materials …

Two human proteins involved in the inflammatory cell death, namely Gasdermin D (GSDMD)
and the Mixed Lineage Kinase Domain-Like (MLKL) protein have been engineered to …

Background Jaw bones are the most common organs to be invaded by oral malignancies,
such as oral squamous cell carcinoma (OSCC), because of their special anatomical …

The sustained release of small, tumor-targeted cytotoxic drugs is an unmet need in cancer
therapies, which usually rely on punctual administration regimens of non-targeted drugs …

The appreciable development in nanotechnology has drawn the attention of several
researchers cutting across different fields. However, some nanoparticles have been …

The last decade has witnessed the blooming of nucleic acids for therapeutic and diagnostic
applications. In the present article, we describe the most important results from our group in …

Simple Summary Aimed at minimizing side toxicities cancer therapies require appropriate
functional vehicles at the nanoscale, for receptor-mediated tumor-targeted drug delivery …

The need for more effective and precision medicines for cancer has pushed the exploration
of new materials appropriate for drug delivery and imaging, and alternative receptors for …