Galectins as modulators of tumour progression

FT Liu, GA Rabinovich - Nature Reviews Cancer, 2005 - nature.com
Galectins are a family of animal lectins with diverse biological activities. They function both
extracellularly, by interacting with cell-surface and extracellular matrix glycoproteins and …

Galectins: structure, function and therapeutic potential

RY Yang, GA Rabinovich, FT Liu - Expert reviews in molecular …, 2008 - cambridge.org
Galectins are a family of animal lectins that bind β-galactosides. Outside the cell, galectins
bind to cell-surface and extracellular matrix glycans and thereby affect a variety of cellular …

Intracellular functions of galectins

FT Liu, RJ Patterson, JL Wang - … et Biophysica Acta (BBA)-General Subjects, 2002 - Elsevier
Many galectin family members are detected primarily intracellularly in most of the systems
studied, although certain members can be found both inside and outside of cells. Specific …

Galectinomics: finding themes in complexity

DNW Cooper - Biochimica et Biophysica Acta (BBA)-General Subjects, 2002 - Elsevier
With the rapid explosion of genomic sequence databases, there has been an equivalent
boom in genomics, the use of sequence information to define and compare gene families …

Galectins and their ligands: amplifiers, silencers or tuners of the inflammatory response?

GA Rabinovich, LG Baum, N Tinari, R Paganelli… - Trends in …, 2002 - cell.com
Recent evidence has implicated galectins and their ligands as master regulators of immune
cell homeostasis. Whereas some members of this family, such as galectin-3, behave as …

[图书][B] Lectins

N Sharon, H Lis - 2003 - books.google.com
This is the second edition of our little red book Lectins published in 1989. In the intervening
years well over 10,000 articles have appeared with lectins as the main subject, and more …

The role of galectins as modulators of metabolism and inflammation

MF Brinchmann, DM Patel… - Mediators of …, 2018 - Wiley Online Library
Galectins are β‐galcotosid‐binding lectins. The function of galectins varies with their tissue‐
specific and subcellular location, and their binding to carbohydrates makes them key players …

Carbohydrate recognition by boronolectins, small molecules, and lectins

S Jin, Y Cheng, S Reid, M Li… - Medicinal research …, 2010 - Wiley Online Library
Carbohydrates are known to mediate a large number of biological and pathological events.
Small and macromolecules capable of carbohydrate recognition have great potentials as …

Integrated functional genomics approach for the design of patient-individual antitumor vaccines

T Weinschenk, C Gouttefangeas, M Schirle… - Cancer research, 2002 - AACR
Our aim is to identify as many candidates as possible for tumor-associated T-cell epitopes in
individual patients. First, we performed expression profiling of tumor and normal tissue to …

Role of galectins in inflammatory and immunomodulatory processes

GA Rabinovich, N Rubinstein, MA Toscano - Biochimica Et Biophysica Acta …, 2002 - Elsevier
Galectins are members of a highly conserved family of β-galactoside-binding animal lectins.
Presently, more than 14 members have been identified and additional homologues are …