[HTML][HTML] Nanosecond SRS fiber amplifier for label-free near-infrared photoacoustic microscopy of lipids

H Lee, MR Seeger, N Lippok, SK Nadkarni… - Photoacoustics, 2022 - Elsevier
Near-infrared photoacoustics receives increasing interest as an intravital modality to sense
key biomolecules. One of the most central types of biomolecules of interest are lipids as they …

Label-free complete absorption microscopy using second generation photoacoustic remote sensing

BR Ecclestone, K Bell, S Sparkes, D Dinakaran… - Scientific Reports, 2022 - nature.com
In the past decades, absorption modalities have emerged as powerful tools for label-free
functional and structural imaging of cells and tissues. Many biomolecules present unique …

Rapid ultraviolet photoacoustic remote sensing microscopy using voice-coil stage scanning

BD Cikaluk, BS Restall, NJM Haven, MT Martell… - Optics …, 2023 - opg.optica.org
There is an unmet need for fast virtual histology technologies that exhibit histological realism
and can scan large sections of fresh tissue within intraoperative time-frames. Ultraviolet …

Photon absorption remote sensing imaging of breast needle core biopsies is diagnostically equivalent to gold standard H&E histologic assessment

JED Tweel, BR Ecclestone, H Gaouda, D Dinakaran… - Current …, 2023 - mdpi.com
Photon absorption remote sensing (PARS) is a new laser-based microscope technique that
permits cellular-level resolution of unstained fresh, frozen, and fixed tissues. Our objective …

Hyperspectral absorption microscopy using photoacoustic remote sensing

K Bell, L Mukhangaliyeva, L Khalili, P Haji Reza - Optics Express, 2021 - opg.optica.org
An improved method of remote optical absorption spectroscopy and hyperspectral optical
absorption imaging is described which takes advantage of the photoacoustic remote …

Multi-channel feature extraction for virtual histological staining of photon absorption remote sensing images

M Boktor, JED Tweel, BR Ecclestone, JA Ye… - Scientific Reports, 2024 - nature.com
Accurate and fast histological staining is crucial in histopathology, impacting diagnostic
precision and reliability. Traditional staining methods are time-consuming and subjective …

Three-dimensional virtual histology in unprocessed resected tissues with photoacoustic remote sensing (PARS) microscopy and optical coherence tomography (OCT)

BR Ecclestone, Z Hosseinaee, N Abbasi, K Bell… - Scientific Reports, 2021 - nature.com
Histological images are critical in the diagnosis and treatment of cancers. Unfortunately,
current methods for capturing these microscopy images require resource intensive tissue …

Virtual hematoxylin and eosin histopathology using simultaneous photoacoustic remote sensing and scattering microscopy

BS Restall, NJM Haven, P Kedarisetti, MT Martell… - Optics …, 2021 - opg.optica.org
Hematoxylin and eosin (H&E) staining is the gold standard for most histopathological
diagnostics but requires lengthy processing times not suitable for point-of-care diagnosis …

Noncontact photoacoustic lipid imaging by remote sensing on first overtone of the CH bond

G Hu, Q Ran, BWL So, M Li, J Shi… - Advanced …, 2023 - spiedigitallibrary.org
Lipid imaging by conventional photoacoustic microscopy subjects to direct contact sensing
with relatively low detection bandwidth and sensitivity, which induces superficial imaging …

Automated Whole Slide Imaging for Label-Free Histology using Photon Absorption Remote Sensing Microscopy

JED Tweel, BR Ecclestone, M Bokto… - IEEE Transactions …, 2024 - ieeexplore.ieee.org
Objective: Pathologists rely on histochemical stains to impart contrast in thin translucent
tissue samples, revealing tissue features necessary for identifying pathological conditions …