Harnessing bioluminescence for drug discovery and epigenetic research
HJ Gleneadie, A Dimond, AG Fisher - Frontiers in Drug Discovery, 2023 - frontiersin.org
The naturally occurring phenomenon of bioluminescence has intrigued on-lookers for
decades and is now being developed as a powerful tool for medical research and preclinical …
decades and is now being developed as a powerful tool for medical research and preclinical …
Protein restriction during pregnancy alters Cdkn1c silencing, dopamine circuitry and offspring behaviour without changing expression of key neuronal marker genes
C Prodani, EE Irvine, A Sardini, HJ Gleneadie… - Scientific Reports, 2024 - nature.com
We tracked the consequences of in utero protein restriction in mice throughout their
development and life course using a luciferase-based allelic reporter of imprinted Cdkn1c …
development and life course using a luciferase-based allelic reporter of imprinted Cdkn1c …
Stability of genomic imprinting and X-chromosome inactivation in the aging brain
Epigenetic drift is a hallmark of aging that contributes to the irreversible decline in
organismal fitness ultimately leading to aging-related diseases. Epigenetic modifications …
organismal fitness ultimately leading to aging-related diseases. Epigenetic modifications …
[PDF][PDF] Exploring the stability of genomic imprinting and X-chromosome inactivation in the aged brain
Changes in the epigenetic landscape are a hallmark of aging that contributes to the
irreversible decline in organismal fitness ultimately leading to aging-related diseases …
irreversible decline in organismal fitness ultimately leading to aging-related diseases …
[引用][C] Chiara Prodani, Elaine E. Irvine 2, Alessandro Sardini 3, Hannah J. Gleneadie, Andrew Dimond, Mathew Van de Pette 4, Rosalind John 5, Michelle Kokkinou 6 …
AG Fisher - Scientific Reports, 2024