The execution of the apoptotic death program in metazoans is characterized by a sequence
of morphological and biochemical changes that include cell shrinkage, presentation of …

Bilirubin has been regarded as a powerful endogenous antioxidant and anti-inflammatory
molecule, able to act on cellular pathways as a hormone. Diabetic kidney disease (DKD) is a …

Background Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia
(AML), which accounts for approximately 10% of all acute myloid leukemia cases. It is a …

We synthesized a new series of conjugated hydrazones that were found to be active against
malaria parasite in vitro, as well as in vivo in a murine model. These hydrazones …

Background: Severe hyperbilirubinemia can cause permanent neurological damage in
particular in neonates, whereas mildly elevated serum bilirubin protects from various …

Background Moderately raised serum bilirubin levels are associated with lower rates of lung
cancer, particularly among smokers. It is not known whether these relationships reflect …

Several recent discoveries of the hallmark features of programmed cell death (PCD) in
Plasmodium falciparum have presented the possibility of revealing novel targets for …

We have investigated the DNA-binding nature as well as the function of a putative Alba
(Acetylation lowers binding affinity) family protein (PfAlba3) from Plasmodium falciparum …

Variation of a short (TA) n repeat sequence (rs8175347) covering the TATA box of UGT1A1
(UDP‐glucuronosyltransferase1A1) is associated with hyperbilirubinaemia (Gilbert's …

Plants are known as the source of novel agents for developing new antimalarial drugs.
Glabridin is a polyphenolic flavonoid, a main constituent in the roots of Glycyrrhiza glabra …