Voltage-gated Ca 2+ channels couple membrane depolarization to Ca 2+-dependent
intracellular signaling events. This is achieved by mediating Ca 2+ ion influx or by direct …

In eukaryotic cells, relaxed interphase chromatin undergoes pronounced changes resulting
in formation of highly condensed mitotic chromosomes. Moreover, chromatin condensation …

In addition to transporting oxygen and carbon dioxide to and from the tissues, a range of
other functions are attributed to red blood cells (RBCs) of vertebrates. Diseases …

Alterations in phosphorylation of cellular proteins are a hallmark of malignant transformation.
Degradation of these phosphoproteins could generate cancer-specific class I MHC …

The vaccinia-related kinases (VRKs) comprise a branch of the casein kinase family whose
members are characterized by homology to the vaccinia virus B1 kinase. The VRK …

Barrier‐to‐autointegration factor (BAF) is an essential, highly conserved, metazoan protein.
BAF interacts with LEM (L AP2, e merin, M AN1) domain‐carrying proteins of the inner …

Mitotic chromatin condensation is essential for cell division in eukaryotes. Posttranslational
modification of the N-terminal tail of histone proteins, particularly by phosphorylation by …

Distal hereditary neuropathies and neuro motor diseases are complex neurological
phenotypes associated with pathogenic variants in a large number of genes, but in some the …

Variations in intracellular levels of p53 regulate many cellular functions and determine tumor
susceptibility. Major mechanisms modulating p53 levels include phosphorylation and …

The accessibility of DNA to different cellular functions requires a dynamic regulation of
chromatin organization that is mediated by different epigenetic modifications, which regulate …