Vitamin D and its active metabolites are important nutrients for human skeletal health. UV
irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the …

Vitamin D status differs by latitude and race, with residents of the northeastern United States
and individuals with more skin pigmentation being at increased risk of deficiency. A PubMed …

Signaling through the vitamin D receptor has been shown to be biologically active and
important in a number of preclinical studies in prostate and other cancers. Epidemiologic …

Abstract 1α, 25-Dihydroxyvitamin D3 [1, 25 (OH) 2D3], the active metabolite of vitamin D, is a
potent inhibitor of breast cancer cell growth. Because the estrogen receptor (ER) plays a key …

During the past few years, it has become apparent that vitamin D may play an important role
in malignant transformation. Epidemiological studies suggest that low vitamin D serum …

OBJECTIVE: Vitamin D is a fat-soluble secosteroid hormone that regulates calcium,
magnesium, and phosphate homeostasis and plays a pivotal role as antiproliferative and …

Context: Uterine fibroids (UFs) are the most common benign tumors in premenopausal
women. In this study, we evaluated the effects of 1, 25-dihydroxyvitamin D3 [1, 25 (OH) 2D3] …

This paper reviews the current understanding of the vitamin D-induced differentiation of
neoplastic cells, which results in the generation of cells that acquire near-normal, mature …

Vitamin D is one of the main groups of sterols; playing an important role in phospho-calcic
metabolism. The conversion of 7-dehydrocholesterol to pre-vitamin D3 in the skin, through …

Colorectal cancer is the third most commonly occurring cancer in the United States and
accounts for∼ 11% of cancer deaths. Many epidemiological studies have shown an …