Biosensing based on field-effect transistors (FET): Recent progress and challenges
D Sadighbayan, M Hasanzadeh… - TrAC Trends in Analytical …, 2020 - Elsevier
The use of field-Effect-Transistor (FET) type biosensing arrangements has been highlighted
by researchers in the field of early biomarker detection and drug screening. Their non …
by researchers in the field of early biomarker detection and drug screening. Their non …
Drug repurposing: a promising tool to accelerate the drug discovery process
Highlights•There is an emerging need for new therapies for rare diseases in a shorter time
frame.•Drug repurposing could arise from serendipitous observations or exploiting side …
frame.•Drug repurposing could arise from serendipitous observations or exploiting side …
Protein-protein interaction modulators: advances, successes and remaining challenges
Modulating disease-relevant protein-protein interactions (PPIs) using small-molecule
inhibitors is a quite indispensable diagnostic and therapeutic strategy in averting …
inhibitors is a quite indispensable diagnostic and therapeutic strategy in averting …
[HTML][HTML] Drug delivery systems in regenerative medicine: an updated review
Modern drug discovery methods led to evolving new agents with significant therapeutic
potential. However, their properties, such as solubility and administration-related …
potential. However, their properties, such as solubility and administration-related …
[HTML][HTML] Brain-on-a-chip: A history of development and future perspective
Since the advent of organ-on-a-chip, many researchers have tried to mimic the physiology of
human tissue on an engineered platform. In the case of brain tissue, structural connections …
human tissue on an engineered platform. In the case of brain tissue, structural connections …
[HTML][HTML] Use of natural products in leishmaniasis chemotherapy: an overview
LFO Gervazoni, GB Barcellos, T Ferreira-Paes… - Frontiers in …, 2020 - frontiersin.org
Leishmaniasis is an infectious parasitic disease that is caused by protozoa of the genus
Leishmania, a member of the Trypanosomatidae family. Leishmaniasis is classified by the …
Leishmania, a member of the Trypanosomatidae family. Leishmaniasis is classified by the …
Low-cost, user-friendly, all-integrated smartphone-based microplate reader for optical-based biological and chemical analyses
The quantitative detection of different molecular targets is of utmost importance for a variety
of human activities, ranging from healthcare to environmental studies. Bioanalytical methods …
of human activities, ranging from healthcare to environmental studies. Bioanalytical methods …
Drug design strategies to avoid resistance in direct-acting antivirals and beyond
Drug resistance is prevalent across many diseases, rendering therapies ineffective with
severe financial and health consequences. Rather than accepting resistance after the fact …
severe financial and health consequences. Rather than accepting resistance after the fact …
[HTML][HTML] Are we seeing a resurgence in the use of natural products for new drug discovery?
F Li, Y Wang, D Li, Y Chen, QP Dou - Expert opinion on drug …, 2019 - Taylor & Francis
The contribution of natural products (NPs) to drug development has been extensively
documented. The structural diversity and biological activity of NPs make them the most …
documented. The structural diversity and biological activity of NPs make them the most …
[HTML][HTML] Marine pharmacology in 2018: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis and antiviral …
AMS Mayer, ML Pierce, K Howe, AD Rodríguez… - Pharmacological …, 2022 - Elsevier
The 2018 marine pharmacology literature review represents a continuation of the previous
11 reviews of a series initiated in 1998. Preclinical marine pharmacology research during …
11 reviews of a series initiated in 1998. Preclinical marine pharmacology research during …