In 2014, FIGO's Committee for Gynecologic Oncology revised the staging of ovarian cancer,
incorporating ovarian, fallopian tube, and peritoneal cancer into the same system. Most of …

Unlike other human cancers, in which all primary tumors arise de novo, ovarian epithelial
cancers are primarily imported from either endometrial or fallopian tube epithelium. The …

High-grade serous ovarian cancer, also known as high-grade serous carcinoma (HGSC), is
the most common and deadliest type of ovarian cancer. HGSC appears to arise from the …

Financial Disclosure Prof. Menon has stock ownership and has received research funding
from Abcodia Ltd, a UCL spinout company with an interest in biomarkers and commercial …

The tumor microenvironment evolves during malignant progression, with major changes in
nonmalignant cells, cytokine networks, and the extracellular matrix (ECM). In this study, we …

Numerous studies have tested the association between TP53 mutations in ovarian cancer
and prognosis but these have been consistently confounded by limitations in study design …

Etiology, transmission and protection: Chlamydia trachomatis is the leading cause of
bacterial sexually transmitted infection (STI) globally. However, C. trachomatis also causes …

Mortality from ovarian cancer may be dramatically reduced with the implementation of
attainable prevention strategies. The new understanding of the cells of origin and the …

Ovarian carcinomas are a heterogeneous group of neoplasms and are traditionally
subclassified based on type and degree of differentiation. Although current clinical …

Although ovarian cancer is the most lethal gynecologic malignancy in women, little is known
about how the cancer initiates and metastasizes. In the last decade, new evidence has …