Chemokines and chemokine receptors: new targets for cancer immunotherapy

V Mollica Poeta, M Massara, A Capucetti… - Frontiers in …, 2019 - frontiersin.org
Immunotherapy is a clinically validated treatment for many cancers to boost the immune
system against tumor growth and dissemination. Several strategies are used to harness …

The effect of hypoxia on the expression of CXC chemokines and CXC chemokine receptors—a review of literature

J Korbecki, K Kojder, P Kapczuk, P Kupnicka… - International journal of …, 2021 - mdpi.com
Hypoxia is an integral component of the tumor microenvironment. Either as chronic or
cycling hypoxia, it exerts a similar effect on cancer processes by activating hypoxia-inducible …

The role of CXCL16 in the pathogenesis of cancer and other diseases

J Korbecki, K Bajdak-Rusinek, P Kupnicka… - International journal of …, 2021 - mdpi.com
CXCL16 is a chemotactic cytokine belonging to the α-chemokine subfamily. It plays a
significant role in the progression of cancer, as well as the course of atherosclerosis, renal …

Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer

AR Farina, L Cappabianca, M Sebastiano… - Journal of Experimental …, 2020 - Springer
Hypoxia-induced alternative splicing is a potent driving force in tumour pathogenesis and
progression. In this review, we update currents concepts of hypoxia-induced alternative …

The role of selected chemokines and their receptors in the development of gliomas

M Groblewska, A Litman-Zawadzka… - International journal of …, 2020 - mdpi.com
Among heterogeneous primary tumors of the central nervous system (CNS), gliomas are the
most frequent type, with glioblastoma multiforme (GBM) characterized with the worst …

[HTML][HTML] CXC family of chemokines as prognostic or predictive biomarkers and possible drug targets in colorectal cancer

S Cabrero-de Las Heras… - World journal of …, 2018 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common cancer in men and the second most
common cancer in women, worldwide. In the early stages of the disease, biomarkers …

Langerhans cells are essential components of the angiogenic niche during murine skin repair

R Wasko, K Bridges, R Pannone, I Sidhu, Y Xing… - Developmental cell, 2022 - cell.com
Angiogenesis, the growth of new blood vessels from pre-existing vessels, occurs during
development, injury repair, and tumorigenesis to deliver oxygen, immune cells, and nutrients …

CXCL16 positively correlated with M2-macrophage infiltration, enhanced angiogenesis, and poor prognosis in thyroid cancer

MJ Kim, HJ Sun, YS Song, SK Yoo, YA Kim, JS Seo… - Scientific Reports, 2019 - nature.com
Although various chemokines have pro-tumorigenic actions in cancers, the effects of
CXCL16 remain controversial. The aim of this study was to investigate the molecular …

Relationship between endothelial and angiogenesis biomarkers envisage mortality in a prospective cohort of COVID-19 patients requiring respiratory support

F Maldonado, D Morales, C Díaz-Papapietro… - Frontiers in …, 2022 - frontiersin.org
Purpose Endothelial damage and angiogenesis are fundamental elements of
neovascularisation and fibrosis observed in patients with coronavirus disease 2019 (COVID …

The role of CXCR1, CXCR2, CXCR3, CXCR5, and CXCR6 ligands in molecular cancer processes and clinical aspects of acute myeloid leukemia (AML)

J Korbecki, P Kupnicka, K Barczak, M Bosiacki… - Cancers, 2023 - mdpi.com
Simple Summary AML is a type of leukemia with a very unfavorable prognosis. Some of the
new therapeutic targets that are being investigated by researchers worldwide are …