Messenger RNA (mRNA) has emerged as a promising therapeutic molecule with numerous
clinical applications in treating central nervous system disorders, tumors, COVID-19, and …

Exosomes are small vesicles containing proteins, nucleic acids, and biological lipids, which
are responsible for intercellular communication. Studies have shown that exosomes can be …

Exosomes are nanoscale extracellular vesicles secreted by cells and enclosed by a lipid
bilayer membrane containing various biologically active cargoes such as proteins, lipids …

Simple Summary Glioblastoma is a highly aggressive brain cancer, and early detection and
accurate diagnosis are crucial for effective treatment. Traditional diagnostic methods have …

Glioblastoma (GBM) stands for the most common and aggressive type of brain tumour in
adults. It is highly invasive, which explains its short rate of survival. Little is known about its …

The increase in the variety of nano-based tools offers new possibilities to approach the
therapy of poorly treatable tumors, which includes glioblastoma multiforme (GBM; a primary …

The mTOR signaling pathway plays a pivotal and intricate role in the pathogenesis of
glioblastoma, driving tumorigenesis and proliferation. Mutations or deletions in the PTEN …

Delivering drugs to the brain is a complex challenge in medical research, particularly for
disorders like Alzheimer's and Parkinson's. The blood–brain barrier restricts the entry of …

Gliomas are brain tumors mainly derived from glial cells that are difficult to treat and cause
high mortality. Radiation, chemotherapy, and surgical excision are the conventional …

Aim: The study aims to improve glioblastoma multiforme (GBM) treatment by combining
temozolomide (TMZ) and quercetin (Qct), using folic acid (FA)-conjugated exosomes to …