The basement membrane is an important extracellular matrix that is found in all epithelial
and endothelial tissues. It maintains tissue integrity, serves as a barrier to cells and to …

Calcium phosphates (CaPs) are among the most utilized synthetic biomaterials for bone
regeneration, largely owing to their established osteoconductive and osteoinductive …

Many existing clinical treatments are limited in their ability to completely restore decreased
or lost tissue and organ function, an unenviable situation only further exacerbated by a …

Abstract Objective Titanium (Ti)-and Zirconia (ZrO 2)-implants in mini pig maxillae were
compared with respect to Ti/zirconium (Zr) release into the surrounding bone tissues, the …

Hypoxia-inducible factor (HIF) signalling is intricately involved in coupling angiogenesis and
osteogenesis during bone development and repair. Activation of HIFs in response to a …

The research paradigm in biomaterials science and engineering is evolving from using low-
throughput and iterative experimental designs towards high-throughput experimental …

Objectives Both excessive and insufficient angiogenesis are associated with progression of
diabetic complications, of which poor angiogenesis is an important feature. Currently …

Intraplaque angiogenesis increases the chance of unstable atherosclerotic plaque rupture
and thrombus formation leading to myocardial infarction. Basic Fibroblast Growth Factor …

Background Proliferative therapy, or prolotherapy, is a controversial treatment method for
many connective tissue injuries and disorders. It involves the injection of a proliferant, or …

Mesenchymal stromal cells (MSCs) are being experimentally tested in several biological
systems and clinical settings with the aim of verifying possible therapeutic effects for a …