Hyaluronate-functionalized hydroxyapatite nanoparticles laden with methotrexate and teriflunomide for the treatment of rheumatoid arthritis

S Pandey, N Rai, A Mahtab, D Mittal, FJ Ahmad… - International Journal of …, 2021 - Elsevier
Rheumatoid arthritis (RA), an autoimmune inflammatory disorder is currently incurable.
Methotrexate and Teriflunomide are routinely prescribed drugs but their uses are limited due …

Quality by design driven development and optimization of teriflunomide loaded nanoliposomes for treatment of rheumatoid arthritis: An in vitro and in vivo …

A Mahtab, M Rizwanullah, S Pandey, A Leekha… - Journal of Drug Delivery …, 2019 - Elsevier
The objective of the present research was to develop teriflunomide-loaded nanoliposomes
by thin-film hydration technique for the management of rheumatoid arthritis. Quality by …

Implementing analytical quality by design in reversed phase-high performance liquid chromatography for simultaneous estimation of teriflunomide and quercetin …

S Karnam, AB Jindal, AT Paul - Journal of Liquid Chromatography …, 2024 - Taylor & Francis
The current study reports the development of a novel, robust, and sensitive reversed-phase
high-performance liquid chromatography (RP-HPLC) method for the simultaneous …

Design and development of bioinspired calcium phosphate nanoparticles of MTX: pharmacodynamic and pharmacokinetic evaluation

S Pandey, A Mahtab, V Kumar… - Drug Development …, 2019 - Taylor & Francis
The aim of this investigation is the management of rheumatoid arthritis (RA) by developing
methotrexate-loaded calcium phosphate nanoparticles (MTX-CAP-NP) and to evaluate …

Development of a validated RP-HPLC assay method for quantitative separation of Teriflunomide and its process-related impurities in bulk drugs

BRB Koppisetty, RP Yejella, AKM Pawar… - Journal of Applied …, 2023 - japsonline.com
The organic, inorganic, and residual solvent impurity sources in pharmacological
compounds have been divided into categories by the International Council for …

STEP TOWORDS THE FORMULATION OF INJECTABLE HYDROGEL: PREFORMULATION STUDIES OF TERIFLUNOMIDE

L Phalke Pallavi - Journal of Pharmaceutical Negative Results, 2022 - pnrjournal.com
Purpose: The aim of formulation of this hydrogel is to treat the osteoarthritis which is one of
the common inflammatory autoimmune disorders of joints. The use of conventional drugs …

Quality by design assisted rp-hplc method for estimation of teriflunomide and its process impurities in drug substance

V Dadi, S Medapati, JK Baratam… - Journal of Faculty of …, 2024 - dergipark.org.tr
Objective: In this research, a validated RP-HPLC method for analyzing teriflunomide drug
substance and its associated process-related impurities was developed with the assistance …