Evolution and strain diversity advance exploration of Candida albicans biology

MZ Anderson, SM Dietz - Msphere, 2024 - journals.asm.org
Fungi were some of the earliest organismal systems used to explore mutational processes
and its phenotypic consequences on members of a species. Yeasts that cause significant …

Candida albicans selection for human commensalism results in substantial within-host diversity without decreasing fitness for invasive disease

FM Anderson, ND Visser, KR Amses… - Plos …, 2023 - journals.plos.org
Candida albicans is a frequent colonizer of human mucosal surfaces as well as an
opportunistic pathogen. C. albicans is remarkably versatile in its ability to colonize diverse …

Molecular Mechanisms of Antimicrobial Resistance in Staphylococcus aureus Biofilms

V Silva, JL Capelo, G Igrejas, P Poeta - Emerging Modalities in Mitigation …, 2022 - Springer
For many decades, Staphylococci have been recognized as the most frequent cause of
biofilm-associated infections. Most antimicrobial resistance research has been focused on …

Bibliometric analysis and thematic review of Candida pathogenesis: Fundamental omics to applications as potential antifungal drugs and vaccines

SJ Lim, ND Muhd Noor, S Sabri… - Medical …, 2024 - academic.oup.com
Invasive candidiasis caused by the pathogenic Candida yeast species has resulted in
elevating global mortality. The pathogenicity of Candida spp. is not only originated from its …

The Effects of Angelica ternata Extract from Kyrgyzstan on the Formation of Candida albicans ATCC 10231 Biofilms

N Sachivkina, A Karamyan, V Semenova, A Ignatiev… - Applied Sciences, 2023 - mdpi.com
The therapeutic potential of Angelica ternata extract was tested against biofilm-associated
fungi Candida albicans. Such an extract with a 1.896±0.071% per 1 mL rutin content of …

Intraspecies transcriptional profiling reveals key regulators of Candida albicans pathogenic traits

JM Wang, AL Woodruff, MJ Dunn, RJ Fillinger… - MBio, 2021 - Am Soc Microbiol
The human commensal and opportunistic fungal pathogen Candida albicans displays
extensive genetic and phenotypic variation across clinical isolates. Here, we performed RNA …

Identification of an active RNAi pathway in Candida albicans

E Iracane, C Arias-Sardá, C Maufrais… - Proceedings of the …, 2024 - National Acad Sciences
RNA interference (RNAi) is a fundamental regulatory pathway with a wide range of
functions, including regulation of gene expression and maintenance of genome stability …

[HTML][HTML] Real-time monitoring of biofilm growth identifies andrographolide as a potent antifungal compound eradicating Candida biofilms

M Žiemytė, JC Rodríguez-Díaz, MP Ventero-Martín… - Biofilm, 2023 - Elsevier
Candida species cause life-threatening infections with high morbidity and mortality rates and
their resistance to conventional therapy is closely linked to biofilm formation. Thus, the …

Crystallographic pattern mediates fungal nanoadhesion bond formation on titanium nanotubes

B Valdez-Salas, E Beltrán-Partida, M Curiel-Alvarez… - ACS …, 2021 - ACS Publications
The development of nanoadhesion bonds at the cell–material biointerface has been
considered as a current prospective mechanism of microbial adhesion and colonization …

Significant variation of filamentation phenotypes in clinical Candida albicans strains

ND Brandquist, C Lampman, EJ Smith… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Candida albicans is an opportunistic human pathogen that typically resides as
part of the microbiome in the gastrointestinal and genitourinary tracts of a large portion of the …