Prostate-specific membrane antigen–targeted therapies for prostate cancer: towards improving therapeutic outcomes

M Corpetti, C Müller, H Beltran, J de Bono… - European urology, 2024 - Elsevier
Context Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein
overexpressed in most prostate cancers and exploited as a target for PSMA-targeted …

Neoadjuvant hormonal therapy before radical prostatectomy in high-risk prostate cancer

G Devos, W Devlies, G De Meerleer… - Nature Reviews …, 2021 - nature.com
Patients with high-risk prostate cancer treated with curative intent are at an increased risk of
biochemical recurrence, metastatic progression and cancer-related death compared with …

Impact of androgen receptor activity on prostate-specific membrane antigen expression in prostate cancer cells

U Sommer, T Siciliano, C Ebersbach… - International Journal of …, 2022 - mdpi.com
Prostate-specific membrane antigen (PSMA) is an essential molecular regulator of prostate
cancer (PCa) progression coded by the FOLH1 gene. The PSMA protein has become an …

Prostate-specific membrane antigen modulates the progression of prostate cancer by regulating the synthesis of arginine and proline and the expression of androgen …

X Hong, L Mao, L Xu, Q Hu, R Jia - Bioengineered, 2022 - Taylor & Francis
The expression of prostate-specific membrane antigen (PSMA) is strikingly upregulated
during oncogenesis and prostate cancer (PCa) progression, but the functions of this antigen …

Consecutive prostate-specific membrane antigen (PSMA) and antigen receptor (AR) PET imaging shows positive correlation with AR and PSMA protein expression in …

V Al Jalali, G Wasinger, S Rasul… - Journal of Nuclear …, 2023 - Soc Nuclear Med
The present study was carried out to investigate whether PET imaging can be used as a
potential substitute for immunohistochemical analysis of tumor samples in prostate cancer …

Consecutive PSMA and AR PET imaging shows positive correlation to AR and PSMA protein expression in primary hormone naïve prostate cancer.

V al Jalali, G Wasinger, S Rasul… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Rationale: The present study set out to investigate if PET imaging can be used as a potential
substitute for immunohistochemical analysis of tumor samples in prostate cancer (PC) …

[HTML][HTML] 血清前列腺特异性抗原联合Gleason 评分对初诊前列腺癌转移风险的预测价值

温健男, 程超, 章泽宇, 左长京 - 第二军医大学学报, 2021 - html.rhhz.net
目的探讨血清前列腺特异性抗原(PSA) 联合活体组织穿刺的Gleason 评分对初诊前列腺癌患者
转移风险的预测价值. 方法回顾性分析2019 年1 月至12 月经前列腺活体组织穿刺病理学初次 …

Development and evaluation of radioimaging agents targeting prostate-specific membrane antigen

KFY Lu - 2023 - open.library.ubc.ca
Prostate-specific membrane antigen (PSMA) is a transmembrane protein with an
extracellular catalytic site that hydrolyzes N-acetylaspartate glutamate. It is associated with …

[HTML][HTML] 初诊前列腺癌患者代谢体积参数与临床指标的相关性

温健男, 程超, 章泽宇, 姜鸿媛, 谷振勇, 左长京 - 第二军医大学学报, 2021 - html.rhhz.net
目的探索初诊前列腺癌(PCa) 患者68 镓标记的前列腺特异性膜抗原(68 Ga-PSMA)-11 PET-CT
的代谢体积参数与临床指标的相关性. 方法回顾性分析2019 年1 月至12 月经前列腺活体组织 …

Evaluating novel prognostic biomarkers in prostate cancer

BS Simpson - 2022 - discovery.ucl.ac.uk
Prostate cancer (PCa) is a major world health issue, killing 358,989 men worldwide each
year. Predicting a disease's likely course (prognosis), is a fundamental question in oncology …