Chalcones as Versatile Synthons for the Synthesis of 5-and 6-membered Nitrogen Heterocycles

H MT Albuquerque, C MM Santos… - Current Organic …, 2014 - ingentaconnect.com
Chalcones belong to the flavonoid family which constitutes one of the major classes of
naturally occurring oxygen heterocyclic compounds. The α, β-unsaturated carbonyl system …

Recent Developments in the Synthesis of Indole‐Pyrazole Hybrids

K Fabitha, M Chandrakanth, RN Pramod… - …, 2022 - Wiley Online Library
Indole and pyrazole are two important scaffolds in the field of medicinal chemistry.
Compounds bearing indole and/or pyrazole moiety have been extensively investigated for a …

Design and efficient synthesis of pyrazoline and isoxazole bridged indole C-glycoside hybrids as potential anticancer agents

P Kumari, VS Mishra, C Narayana, A Khanna… - Scientific reports, 2020 - nature.com
C-glycosides are important class of molecules exhibit diverse biological activities and
present as structural motif in many natural products. Two series of new pyrazoline and …

Synthesis, spectroscopic and DFT studies of 5-methyl-1H-pyrazole-3-carbohydrazide N-glycoside as potential anti-diabetic and antioxidant agent

S Mortada, SA Brandán, K Karrouchi… - Journal of Molecular …, 2022 - Elsevier
A novel pyrazole-carbohydrazide N-glycoside derivative (SM1) was prepared by
condensation of D-glucose with 1H-pyrazole-3-carbohydrazide. The structure of SM1 was …

Design and synthesis of sugar-triazole low molecular weight gels as mercury ion sensor

A Hemamalini, TM Das - New Journal of Chemistry, 2013 - pubs.rsc.org
A series of gel forming symmetrical bis-sugar-triazoles has been developed for the
recognition of Hg2+ ions. Preferential interaction of Hg2+ ions with organogelator based …

Diastereoselective synthesis, characterization, investigation of anticancer, antibacterial activities, in silico approaches and DNA/BSA binding affinities of novel …

N Kahriman, V Serdaroğlu, A Aydın… - Journal of Molecular …, 2023 - Elsevier
ABSTRACT Eighteen novel carbohydrate conjugates (1-9) and their tetra-O-acetyl
derivatives (10-18) were synthesized in total and evaluated for their biological properties …

Indolylvinyl ketones: Building blocks for the synthesis of natural products and bioactive compounds

IV Trushkov, MG Uchuskin, VT Abaev, OV Serdyuk - Synthesis, 2019 - thieme-connect.com
Indolylvinyl ketones are valuable building blocks that can be utilized for the synthesis of
numerous natural products and bioactive molecules containing an indole core motif. Herein …

The long underestimated carbonyl function of carbohydrates–an organocatalyzed shot into carbohydrate chemistry

R Mahrwald - Chemical Communications, 2015 - pubs.rsc.org
The aggressive and strong development of organocatalysis provides several protocols for
the convenient utilization of the carbonyl function of unprotected carbohydrates in C–C-bond …

From 2011 to 2022: The development of pyrazole derivatives through the α,β‐unsaturated carbonyl compounds

S Sharma, V Singh, Vaishali, R Kumar… - Journal of …, 2024 - Wiley Online Library
The synthesis of pyrazole derivative using α, β‐unsaturated carbonyl compounds has
attracted increasing attention of the synthetic organic chemist community. Interestingly, the …

Microwave-assisted rapid synthesis of sugar-based pyrazole derivatives with anticancer activity in water

K Du, C Xia, M Wei, X Chen, P Zhang - RSC advances, 2016 - pubs.rsc.org
Microwave-assisted rapid synthesis of sugar-based pyrazole derivatives with anticancer activity
in water - RSC Advances (RSC Publishing) DOI:10.1039/C6RA05284C Royal Society of …