Zebrafish as a Model for Osteoporosis: Functional Validations of Genome-Wide Association Studies
I Ben-Zvi, D Karasik, CL Ackert-Bicknell - Current Osteoporosis Reports, 2023 - Springer
Purpose of Review GWAS, as a largely correlational analysis, requires in vitro or in vivo
validation. Zebrafish (Danio rerio) have many advantages for studying the genetics of …
validation. Zebrafish (Danio rerio) have many advantages for studying the genetics of …
Size and locomotor ecology have differing effects on the external and internal morphologies of squirrel (Rodentia: Sciuridae) limb bones
J Rickman, AE Burtner, TJ Linden… - Integrative …, 2023 - academic.oup.com
Mammals exhibit a diverse range of limb morphologies that are associated with different
locomotor ecologies and structural mechanics. Much remains to be investigated, however …
locomotor ecologies and structural mechanics. Much remains to be investigated, however …
Whole‐Exome Sequencing Analysis Identifies Risk Genes in Atlantoaxial Dislocation Patients with Sandwich Fusion
G Gao, Y Tian, KL Hung, D Fan, N Xu… - Human Mutation, 2024 - Wiley Online Library
Sandwich fusion of Klippel‐Feil syndrome (KFS), which is a rare congenital disorder
involving the fusion of cervical vertebrae, poses significant challenges in the diagnosis and …
involving the fusion of cervical vertebrae, poses significant challenges in the diagnosis and …
Loss of cped1 does not affect bone and lean tissue in zebrafish
K Alvarado, WJ Tang, CJ Watson, AR Ahmed… - JBMR plus, 2025 - academic.oup.com
Human genetic studies have nominated cadherin-like and PC-esterase domain-containing 1
(CPED1) as a candidate target gene mediating bone mineral density (BMD) and fracture risk …
(CPED1) as a candidate target gene mediating bone mineral density (BMD) and fracture risk …
Dominant nonsense mutations in efemp1 alter vertebral and craniofacial characteristics in adult zebrafish
Abstract Heritable Disorders of Connective Tissues (HDCT) are a heterogenous, pleiotropic
group of conditions that broadly affect connective tissues. EFEMP1 is a member of the fibulin …
group of conditions that broadly affect connective tissues. EFEMP1 is a member of the fibulin …