The endothelium, by area alone, is one of the largest organs in the body comprised of up to
trillion cells, weighing over 1 kg, and covering nearly 3 m2 in a 70 kg male. 1, 2 Moreover, it …

Most acute coronary syndromes are caused by sudden luminal thrombosis due to
atherosclerotic plaque rupture or erosion. Preventing such an event seems to be the only …

Background We hypothesized that in patients with stable coronary artery disease and
stenosis, percutaneous coronary intervention (PCI) performed on the basis of the fractional …

Objectives: The goal of this study was to determine the diagnostic performance of
noninvasive fractional flow reserve (FFR) derived from standard acquired coronary …

Background The preferred initial treatment for patients with stable coronary artery disease is
the best available medical therapy. We hypothesized that in patients with functionally …

Aims The present analysis addresses the potential clinical and physiologic significance of
discordance in severity of coronary artery disease between the angiogram and fractional …

Background—The predictive value of fractional flow reserve (FFR) measured immediately
after percutaneous coronary intervention (PCI) with drug-eluting stent placement has not …

Background: In patients with coronary artery disease, clinical outcome depends on the
extent of reversible myocardial ischemia. Whether the outcome also depends on the severity …

Objectives: This study sought to compare fractional flow reserve (FFR) with the
instantaneous wave-free ratio (iFR) in patients with coronary artery disease and also to …

Background—Fractional flow reserve (FFR) measurement of intermediate coronary stenoses
is recommended by guidelines when demonstration of ischemia by noninvasive testing is …