Y Cai, J Qi, Y Lu, H He, W Wu - Advanced Drug Delivery Reviews, 2022 - Elsevier
This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …
The blood-brain barrier (BBB) has been a great hurdle for brain drug delivery. The BBB in healthy brain is a diffusion barrier essential for protecting normal brain function by impeding …
Micelles have been studied as drug delivery carriers for decades. Their use can potentially result in high drug accumulation at the target site through the enhanced permeability and …
M Dessale, G Mengistu, HM Mengist - International Journal of …, 2022 - ncbi.nlm.nih.gov
Cancer remains the most devastating disease and the major cause of mortality worldwide. Although early diagnosis and treatment are the key approach in fighting against cancer, the …
Background: Nanotechnology is gaining significant attention worldwide for cancer treatment. Nanobiotechnology encourages the combination of diagnostics with therapeutics, which is a …
A Reisch, AS Klymchenko - Small, 2016 - Wiley Online Library
Speed, resolution and sensitivity of today's fluorescence bioimaging can be drastically improved by fluorescent nanoparticles (NPs) that are many‐fold brighter than organic dyes …
JH Lee, Y Yeo - Chemical engineering science, 2015 - Elsevier
Nanocarriers providing spatiotemporal control of drug release contribute to reducing toxicity and improving therapeutic efficacy of a drug. On the other hand, nanocarriers face unique …
YH Bae, K Park - Journal of controlled release, 2011 - Elsevier
The ultimate goal of drug delivery research is to help patients by developing clinically useful formulations. During the last several decades controlled drug delivery technology has …
Polymeric micelles provide a platform that can be carefully tuned for drug delivery. The nano- scale aggregates form spontaneously in aqueous solution and can be used to overcome …