[HTML][HTML] Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions

M Ghezzi, S Pescina, C Padula, P Santi… - Journal of Controlled …, 2021 - Elsevier
Polymeric micelles, ie aggregation colloids formed in solution by self-assembling of
amphiphilic polymers, represent an innovative tool to overcome several issues related to …

The in vivo fate of polymeric micelles

Y Cai, J Qi, Y Lu, H He, W Wu - Advanced Drug Delivery Reviews, 2022 - Elsevier
This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …

[HTML][HTML] Current strategies for brain drug delivery

X Dong - Theranostics, 2018 - ncbi.nlm.nih.gov
The blood-brain barrier (BBB) has been a great hurdle for brain drug delivery. The BBB in
healthy brain is a diffusion barrier essential for protecting normal brain function by impeding …

Strategies to improve micelle stability for drug delivery

Y Lu, E Zhang, J Yang, Z Cao - Nano research, 2018 - Springer
Micelles have been studied as drug delivery carriers for decades. Their use can potentially
result in high drug accumulation at the target site through the enhanced permeability and …

[HTML][HTML] Nanotechnology: a promising approach for cancer diagnosis, therapeutics and theragnosis

M Dessale, G Mengistu, HM Mengist - International Journal of …, 2022 - ncbi.nlm.nih.gov
Cancer remains the most devastating disease and the major cause of mortality worldwide.
Although early diagnosis and treatment are the key approach in fighting against cancer, the …

Cancer nanotechnology: a new revolution for cancer diagnosis and therapy

VK Chaturvedi, A Singh, VK Singh… - Current drug …, 2019 - ingentaconnect.com
Background: Nanotechnology is gaining significant attention worldwide for cancer treatment.
Nanobiotechnology encourages the combination of diagnostics with therapeutics, which is a …

Fluorescent polymer nanoparticles based on dyes: seeking brighter tools for bioimaging

A Reisch, AS Klymchenko - Small, 2016 - Wiley Online Library
Speed, resolution and sensitivity of today's fluorescence bioimaging can be drastically
improved by fluorescent nanoparticles (NPs) that are many‐fold brighter than organic dyes …

Controlled drug release from pharmaceutical nanocarriers

JH Lee, Y Yeo - Chemical engineering science, 2015 - Elsevier
Nanocarriers providing spatiotemporal control of drug release contribute to reducing toxicity
and improving therapeutic efficacy of a drug. On the other hand, nanocarriers face unique …

Targeted drug delivery to tumors: myths, reality and possibility

YH Bae, K Park - Journal of controlled release, 2011 - Elsevier
The ultimate goal of drug delivery research is to help patients by developing clinically useful
formulations. During the last several decades controlled drug delivery technology has …

Polymeric micelle stability

SC Owen, DPY Chan, MS Shoichet - Nano today, 2012 - Elsevier
Polymeric micelles provide a platform that can be carefully tuned for drug delivery. The nano-
scale aggregates form spontaneously in aqueous solution and can be used to overcome …