Mechanical thrombectomy for acute ischemic stroke in octogenarians: a systematic review and meta-analysis

W Zhao, P Ma, P Zhang, X Yue - Frontiers in neurology, 2020 - frontiersin.org
Background and purpose: Multiple randomized trials have confirmed that mechanical
thrombectomy (MT) is an effective treatment method for patients with acute ischemic stroke …

Functional outcomes of patients≥ 85 years with acute ischemic stroke following EVT: a HERMES substudy

RV McDonough, JM Ospel, BCV Campbell, MD Hill… - Stroke, 2022 - Am Heart Assoc
Background: Observational studies have shown endovascular treatment (EVT) for acute
ischemic stroke to be effective in the elderly, despite resulting in poorer outcomes and …

Brain atrophy and the risk of futile endovascular reperfusion in acute ischemic stroke

MI Pedraza, M de Lera, D Bos, AI Calleja, E Cortijo… - Stroke, 2020 - Am Heart Assoc
Background and Purpose—We aimed to evaluate the impact of brain atrophy on long-term
clinical outcome in patients with acute ischemic stroke treated with endovascular therapy …

[HTML][HTML] Clinical frailty and outcome after mechanical thrombectomy for stroke in patients aged≥ 80 years

M Tiainen, N Martinez-Majander, P Virtanen… - Journal of Stroke and …, 2022 - Elsevier
Objectives Data concerning the results of endovascular thrombectomy (EVT) in old patients
is still limited. We aimed to investigate the outcomes in thrombectomy-treated ischemic …

Is endovascular treatment still good for acute ischemic stroke in the elderly? A meta-analysis of observational studies in the last decade

X Jiang, J Wang, Y Hu, H Lang, J Bao… - Frontiers in …, 2024 - frontiersin.org
Background The lack of randomized evidence makes it difficult to establish reliable
treatment recommendations for endovascular treatment (EVT) in elderly patients. This meta …

[HTML][HTML] Impact of age on mechanical thrombectomy and clinical outcome in patients with acute ischemic stroke

N Rhiner, MZ Thut, P Thurner, J Madjidyar… - Journal of Stroke and …, 2023 - Elsevier
Background and purpose Mechanical thrombectomy is less effective in patients aged 80
years or older. Our goal was to better understand the impact of age in general on …

Mediation of age and Thrombectomy outcome by neuroimaging markers of frailty in patients with stroke

F Benali, N Singh, J Fladt… - JAMA Network …, 2024 - jamanetwork.com
Importance Age is a leading predictor of poor outcomes after brain injuries like stroke. The
extent to which age is associated with preexisting burdens of brain changes, visible on …

Safety and efficacy of tenecteplase in older patients with large vessel occlusion: a pooled analysis of the EXTEND-IA TNK trials

V Yogendrakumar, L Churilov, PJ Mitchell, TJ Kleinig… - Neurology, 2022 - AAN Enterprises
Background and Objectives Detailed study of tenecteplase (TNK) in patients older than 80
years is limited. The objective of our study was to assess the safety and efficacy of TNK at …

Effect of age and baseline ASPECTS on outcomes in large-vessel occlusion stroke: results from the HERMES collaboration

JM Ospel, M Kappelhof, N Kashani… - Journal of …, 2021 - jnis.bmj.com
Background Patient age and baseline Alberta Stroke Program Early CT score (ASPECTS)
are both independent predictors of outcome in acute ischemic stroke patients treated with …

Innovation in Acute Ischemic Stroke Patients over 80 y/o—A Retrospective Monocentric Study on Mechanical Thrombectomy of Consecutive Patients: Is Age an …

M Cernigliaro, C Stanca, A Galbiati, M Spinetta… - Journal of Clinical …, 2023 - mdpi.com
Background: Although it is clear that stroke is a time-dependent and age-associated
disease, we still need more evidence regarding the efficacy and outcomes in elderly patients …