[HTML][HTML] Genome regulation by polycomb and trithorax: 70 years and counting

B Schuettengruber, HM Bourbon, L Di Croce, G Cavalli - Cell, 2017 - cell.com
Polycomb (PcG) and Trithorax (TrxG) group proteins are evolutionarily conserved chromatin-
modifying factors originally identified as part of an epigenetic cellular memory system that …

Polycomb and Trithorax Group Genes in Drosophila

JA Kassis, JA Kennison, JW Tamkun - Genetics, 2017 - academic.oup.com
Abstract Polycomb group (PcG) and Trithorax group (TrxG) genes encode important
regulators of development and differentiation in metazoans. These two groups of genes …

Modular organization and assembly of SWI/SNF family chromatin remodeling complexes

N Mashtalir, AR D'Avino, BC Michel, J Luo, J Pan… - Cell, 2018 - cell.com
Summary Mammalian SWI/SNF (mSWI/SNF) ATP-dependent chromatin remodeling
complexes are multi-subunit molecular machines that play vital roles in regulating genomic …

Chromatin remodelling during development

L Ho, GR Crabtree - Nature, 2010 - nature.com
New methods for the genome-wide analysis of chromatin are providing insight into its roles
in development and their underlying mechanisms. Current studies indicate that chromatin is …

The coregulator exchange in transcriptional functions of nuclear receptors

CK Glass, MG Rosenfeld - Genes & development, 2000 - genesdev.cshlp.org
Nuclear receptors (NR) comprise a family of transcription factors that regulate gene
expression in a liganddependent manner. Members of the NR superfamily include receptors …

Germ-Line and Acquired Mutations of INI1 in Atypical Teratoid and Rhabdoid Tumors

JA Biegel, JY Zhou, LB Rorke, C Stenstrom… - Cancer research, 1999 - AACR
We examined 18 atypical teratoid and rhabdoid tumors of the brain and 7 renal and 4
extrarenal rhabdoid tumors for mutations in the candidate rhabdoid tumor suppressor gene …

Purification and biochemical heterogeneity of the mammalian SWI‐SNF complex.

W Wang, J Côté, Y Xue, S Zhou, PA Khavari… - The EMBO …, 1996 - embopress.org
We have purified distinct complexes of nine to 12 proteins [referred to as BRG1‐associated
factors (BAFs)] from several mammalian cell lines using an antibody to the SWI2‐SNF2 …

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes

S Bultman, T Gebuhr, D Yee, C La Mantia, J Nicholson… - Molecular cell, 2000 - cell.com
Mammalian SWI/SNF complexes utilize either brahma (Brm) or brahma-related gene 1
(Brg1) catalytic subunits to remodel nucleosomes in an ATP-dependent manner. Brm was …

The BAF complex in development and disease

A Alfert, N Moreno, K Kerl - Epigenetics & chromatin, 2019 - Springer
The ATP-dependent chromatin remodelling complex BAF (= mammalian SWI/SNF complex)
is crucial for the regulation of gene expression and differentiation. In the course of evolution …

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits

ML Phelan, S Sif, GJ Narlikar, RE Kingston - Molecular cell, 1999 - cell.com
Protein complexes of the SWI/SNF family remodel nucleosome structure in an ATP-
dependent manner. Each complex contains between 8 and 15 subunits, several of which …