Getting neural circuits into shape with semaphorins

RJ Pasterkamp - Nature Reviews Neuroscience, 2012 - nature.com
Semaphorins are key players in the control of neural circuit development. Recent studies
have uncovered several exciting and novel aspects of neuronal semaphorin signalling in …

Semaphorin signalling during development

BC Jongbloets, RJ Pasterkamp - Development, 2014 - journals.biologists.com
Semaphorins are secreted and membrane-associated proteins that regulate many different
developmental processes, including neural circuit assembly, bone formation and …

MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation

CJ Li, P Cheng, MK Liang, YS Chen… - The Journal of …, 2015 - Am Soc Clin Investig
Bone marrow mesenchymal stem cells (BMSCs) exhibit an age-dependent reduction in
osteogenesis that is accompanied by an increased propensity toward adipocyte …

APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p

K Wang, CY Liu, LY Zhou, JX Wang, M Wang… - Nature …, 2015 - nature.com
The abnormal autophagy is associated with a variety of cardiovascular diseases. Long
noncoding RNAs (lncRNAs) are emerging as new factors in gene regulation, but how …

[HTML][HTML] MicroRNAs shape the neuronal landscape

E McNeill, D Van Vactor - Neuron, 2012 - cell.com
The nervous system equips us with capability to adapt to many conditions and
circumstances. We rely on an armamentarium of intricately formed neural circuits for many of …

How the epigenome integrates information and reshapes the synapse

RR Campbell, MA Wood - Nature Reviews Neuroscience, 2019 - nature.com
In the past few decades, the field of neuroepigenetics has investigated how the brain
encodes information to form long-lasting memories that lead to stable changes in behaviour …

MicroRNA-188-5p suppresses tumor cell proliferation and metastasis by directly targeting FGF5 in hepatocellular carcinoma

F Fang, R Chang, L Yu, X Lei, S Xiao, H Yang… - Journal of …, 2015 - Elsevier
Background & Aims Hepatocellular carcinoma (HCC) is one of the most common
malignancies worldwide. However, the detailed molecular mechanisms underlying HCC …

miRNAs in synapse development and synaptic plasticity

Z Hu, Z Li - Current opinion in neurobiology, 2017 - Elsevier
Highlights•miRNAs and RISC are located near synapses.•miRNAs regulate local protein
synthesis in dendrites and axons.•miRNAs play important roles in synapse development and …

Linking deregulation of non-coding RNA to the core pathophysiology of Alzheimer's disease: An integrative review

MJ Millan - Progress in neurobiology, 2017 - Elsevier
The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …

MicroRNAs in age‐related diseases

S Dimmeler, P Nicotera - EMBO molecular medicine, 2013 - embopress.org
Aging is a complex process that is linked to an increased incidence of major diseases such
as cardiovascular and neurodegenerative disease, but also cancer and immune disorders …