Multi-omic data integration and analysis using systems genomics approaches: methods and applications in animal production, health and welfare

P Suravajhala, LJA Kogelman… - Genetics Selection …, 2016 - Springer
In the past years, there has been a remarkable development of high-throughput omics (HTO)
technologies such as genomics, epigenomics, transcriptomics, proteomics and …

The mammalian preimplantation embryo: its role in the environmental programming of postnatal health and performance

MA Velazquez, A Idriss, P Chavatte-Palmer… - Animal Reproduction …, 2023 - Elsevier
During formation of the preimplantation embryo several cellular and molecular milestones
take place, making the few cells forming the early embryo vulnerable to environmental …

Establishment of bovine expanded potential stem cells

L Zhao, X Gao, Y Zheng, Z Wang… - Proceedings of the …, 2021 - National Acad Sciences
Embryonic stem cells (ESCs) and induced pluripotent stem cells have the potential to
differentiate to all cell types of an adult individual and are useful for studying development …

An oviduct-on-a-chip provides an enhanced in vitro environment for zygote genome reprogramming

MAMM Ferraz, HS Rho, D Hemerich… - Nature …, 2018 - nature.com
Worldwide over 5 million children have been conceived using assisted reproductive
technology, and research has concentrated on increasing the likelihood of ongoing …

H3K9 demethylase KDM4E is an epigenetic regulator for bovine embryonic development and a defective factor for nuclear reprogramming

X Liu, Y Wang, Y Gao, J Su, J Zhang, X Xing… - …, 2018 - journals.biologists.com
Aberrant epigenetic reprogramming often results in developmental defects in somatic cell
nuclear transfer (SCNT) embryos during embryonic genome activation (EGA). Bovine eight …

Dynamics of trophoblast differentiation in peri-implantation–stage human embryos

RC West, H Ming, DM Logsdon, J Sun… - Proceedings of the …, 2019 - National Acad Sciences
Single-cell RNA sequencing of cells from cultured human blastocysts has enabled us to
define the transcriptomic landscape of placental trophoblast (TB) that surrounds the epiblast …

The proteomic analysis of bovine embryos developed in vivo or in vitro reveals the contribution of the maternal environment to early embryo

C Banliat, C Mahé, R Lavigne, E Com, C Pineau… - BMC genomics, 2022 - Springer
Background Despite many improvements with in vitro culture systems, the quality and
developmental ability of mammalian embryos produced in vitro are still lower than their in …

MicroRNA expression during bovine oocyte maturation and fertilization

GC Gilchrist, A Tscherner, T Nalpathamkalam… - International journal of …, 2016 - mdpi.com
Successful fertilization and subsequent embryo development rely on complex molecular
processes starting with the development of oocyte competence through maturation …

Embryo competence and cryosurvival: Molecular and cellular features

TV Marsico, J Camargo, RS Valente… - Animal Reproduction, 2019 - SciELO Brasil
Global cattle genetic market is experiencing a change of strategy, large genetic companies,
traditionally recognized in the artificial insemination field, have also begun to operate in the …

Why is it so difficult to have competent oocytes from in vitro cultured preantral follicles?

LRFM Paulino, EIT de Assis, VAN Azevedo… - Reproductive …, 2022 - Springer
The developmental competence of oocytes is acquired gradually during follicular
development, mainly through oocyte accumulation of RNA molecules and proteins that will …