The brain is an information processing machine and thus naturally lends itself to be studied
using computational tools based on the principles of information theory. For this reason …

NMDA receptors (NMDARs) have been proposed to control single-neuron computations in
vivo. However, whether specific mechanisms regulate the function of such receptors and …

A basic—yet nontrivial—function which neocortical circuitry must satisfy is the ability to
maintain stable spiking activity over time. Stable neocortical activity is asynchronous, critical …

The electroencephalogram (EEG) is a major tool for non-invasively studying brain function
and dysfunction. Comparing experimentally recorded EEGs with neural network models is …

The sensory cortex amplifies relevant features of external stimuli. This sensitivity and
selectivity arise through the transformation of inputs by cortical circuitry. We characterize the …

Perisomatic inhibition of pyramidal neurons (PNs) coordinates cortical network activity
during sensory processing, and this role is mainly attributed to parvalbumin-expressing …

Unbiased and dense sampling of large populations of layer 2/3 pyramidal neurons in mouse
primary visual cortex (V1) reveals two functional sub-populations: neurons tuned and …

Interneurons (INs), specifically those in disinhibitory circuits like somatostatin (SST) and
vasoactive intestinal peptide (VIP)-INs, are strongly modulated by the behavioral context …

Chaotic dynamics have been evidenced in experimental data and numerical simulations
ranging from the most straightforward individual neurons to the more complex neural …

The spiking activity of neocortical neurons exhibits a striking level of variability, even when
these networks are driven by identical stimuli. The approximately Poisson firing of neurons …