microRNAs: new prognostic, diagnostic, and therapeutic biomarkers in cervical cancer

JS Nahand, S Taghizadeh‐boroujeni… - Journal of cellular …, 2019 - Wiley Online Library
Cervical cancer is as a kind of cancer beginning from the cervix. Given that cervical cancer
could be observed in women who infected with papillomavirus, regular oral contraceptives …

Mechanisms of taxane resistance

SM Maloney, CA Hoover, LV Morejon-Lasso… - Cancers, 2020 - mdpi.com
Simple Summary Drug resistance is prevalent in many types of cancer and decreases
patient survival. The taxanes are anti-mitotic chemotherapeutic agents, widely used since …

Epigenetics and cervical cancer: from pathogenesis to therapy

J Fang, H Zhang, S Jin - Tumor Biology, 2014 - Springer
Although human papillomavirus (HPV) infection has been found in most of the cervical
cancer cases, additional genetic and epigenetic changes are required for disease …

miR‐372 suppresses tumour proliferation and invasion by targeting IGF 2 BP 1 in renal cell carcinoma

X Huang, M Huang, L Kong, Y Li - Cell proliferation, 2015 - Wiley Online Library
Objectives Micro RNA s (mi RNA s) are endogenous small non‐coding RNA s that regulate
proteins and mRNA s for degradation or translational suppression. Up to now, the role of …

Increased exosomal microRNA-21 and microRNA-146a levels in the cervicovaginal lavage specimens of patients with cervical cancer

J Liu, H Sun, X Wang, Q Yu, S Li, X Yu… - International journal of …, 2014 - mdpi.com
Well-run screening programs for cervical cancer in the population at risk have been shown
to result in a sharp decrease in the incidence and mortality of cervical cancer in a number of …

Serum microRNA expression levels can predict lymph node metastasis in patients with early-stage cervical squamous cell carcinoma

J Chen, D Yao, Y Li, H Chen, C He… - International …, 2013 - spandidos-publications.com
Circulating microRNA expression levels can serve as diagnostic/prognostic biomarkers in
several types of malignant tumors; however, to our knowledge, there have been reports …

MicroRNA-10a targets CHL1 and promotes cell growth, migration and invasion in human cervical cancer cells

MJ Long, FX Wu, P Li, M Liu, X Li, H Tang - Cancer letters, 2012 - Elsevier
MicroRNAs (miRNAs) play an important role in cancer initiation, progression and metastasis
by regulating their target genes. Here, we found microRNA-10a (miR-10a) is upregulated in …

Epigenetic alterations in human papillomavirus-associated cancers

D Soto, C Song, ME McLaughlin-Drubin - Viruses, 2017 - mdpi.com
Approximately 15–20% of human cancers are caused by viruses, including human
papillomaviruses (HPVs). Viruses are obligatory intracellular parasites and encode proteins …

MicroRNAs in gynecological cancers: Small molecules with big implications

SK Srivastava, A Ahmad, H Zubair, O Miree, S Singh… - Cancer letters, 2017 - Elsevier
Gynecological cancers (GCs) are often diagnosed at advanced stages, limiting the efficacy
of available therapeutic options. Thus, there remains an urgent and unmet need for …

Overexpression of miR-21 promotes the proliferation and migration of cervical cancer cells via the inhibition of PTEN

J Xu, W Zhang, Q Lv, D Zhu - Oncology reports, 2015 - spandidos-publications.com
The oncogenic miR-21 has been widely recognized to promote the development and
progression of various types of malignant tumors, but not cervical cancers. The aim of this …