Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents

A Najmi, SA Javed, M Al Bratty, HA Alhazmi - Molecules, 2022 - mdpi.com
Natural products represents an important source of new lead compounds in drug discovery
research. Several drugs currently used as therapeutic agents have been developed from …

Advances in fingerprint analysis for standardization and quality control of herbal medicines

E Noviana, G Indrayanto, A Rohman - Frontiers in Pharmacology, 2022 - frontiersin.org
Herbal drugs or herbal medicines (HMs) have a long-standing history as natural remedies
for preventing and curing diseases. HMs have garnered greater interest during the past …

Aristolochic acid-associated cancers: a public health risk in need of global action

S Das, S Thakur, M Korenjak, VS Sidorenko… - Nature Reviews …, 2022 - nature.com
Aristolochic acids (AAs) are a group of naturally occurring compounds present in many plant
species of the Aristolochiaceae family. Exposure to AA is a significant risk factor for severe …

DNA barcoding: an efficient technology to authenticate plant species of traditional Chinese medicine and recent advances

S Zhu, Q Liu, S Qiu, J Dai, X Gao - Chinese Medicine, 2022 - Springer
Traditional Chinese medicine (TCM) plays an important role in the global traditional health
systems. However, adulterated and counterfeit TCM is on the rise. DNA barcoding is an …

Benefits and limitations of DNA barcoding and metabarcoding in herbal product authentication

AC Raclariu, M Heinrich, MC Ichim… - Phytochemical …, 2018 - Wiley Online Library
Introduction Herbal medicines play an important role globally in the health care sector and in
industrialised countries they are often considered as an alternative to mono‐substance …

DNA barcoding for the identification of botanicals in herbal medicine and dietary supplements: strengths and limitations

I Parveen, S Gafner, N Techen, SJ Murch… - Planta …, 2016 - thieme-connect.com
In the past decades, the use of traditional medicine has increased globally, leading to a
booming herbal medicine and dietary supplement industry. The increased popularity of …

The DNA-based authentication of commercial herbal products reveals their globally widespread adulteration

MC Ichim - Frontiers in pharmacology, 2019 - frontiersin.org
The herbal products, sold worldwide as medicines or foods, are perceived as low risk
because they are considered natural and thus safe. The quality of these products is …

DNA mini-barcoding: a derived barcoding method for herbal molecular identification

Z Gao, Y Liu, X Wang, X Wei, J Han - Frontiers in plant science, 2019 - frontiersin.org
In recent years, the demand for natural herbal products (NHP) has increased; however, the
quality of these products is difficult to confirm due to the lack of a comprehensive quality …

Quality control of herbal medicines: From traditional techniques to state-of-the-art approaches

LC Klein-Junior, MR de Souza, J Viaene… - Planta …, 2021 - thieme-connect.com
Herbal medicines are important options for the treatment of several illnesses. Although their
therapeutic applicability has been demonstrated throughout history, several concerns about …

Botanical origin authentication of dietary supplements by DNA‐based approaches

L Grazina, JS Amaral, I Mafra - Comprehensive Reviews in …, 2020 - Wiley Online Library
Herbal products, such as dietary supplements, have become a subject of increasing global
importance for their health benefits and economic considerations. However, they have also …