[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …
The biological and clinical significance of emerging SARS-CoV-2 variants
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India
Delhi, the national capital of India, experienced multiple severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) outbreaks in 2020 and reached population seropositivity of> …
coronavirus 2 (SARS-CoV-2) outbreaks in 2020 and reached population seropositivity of> …
Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation
BJ Fraser, S Beldar, A Seitova, A Hutchinson… - Nature chemical …, 2022 - nature.com
Abstract Transmembrane protease, serine 2 (TMPRSS2) has been identified as key host cell
factor for viral entry and pathogenesis of SARS-CoV-2. Specifically, TMPRSS2 …
factor for viral entry and pathogenesis of SARS-CoV-2. Specifically, TMPRSS2 …
Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity
INTRODUCTION Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) have been circulating worldwide since the beginning of the pandemic. Some are termed …
2) have been circulating worldwide since the beginning of the pandemic. Some are termed …
Mutations and evolution of the SARS-CoV-2 spike protein
The SARS-CoV-2 spike protein mediates target recognition, cellular entry, and ultimately the
viral infection that leads to various levels of COVID-19 severities. Positive evolutionary …
viral infection that leads to various levels of COVID-19 severities. Positive evolutionary …
Structural impact on SARS-CoV-2 spike protein by D614G substitution
Substitution for aspartic acid (D) by glycine (G) at position 614 in the spike (S) protein of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears to facilitate rapid …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears to facilitate rapid …
SARS-COV-2 variants: differences and potential of immune evasion
SM Hirabara, TDA Serdan, R Gorjao… - Frontiers in cellular …, 2022 - frontiersin.org
The structural spike (S) glycoprotein of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) plays an essential role in infection and is an important target for neutralizing …
(SARS-CoV-2) plays an essential role in infection and is an important target for neutralizing …
Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain
The omicron variant of SARS-CoV-2 has been spreading rapidly across the globe. The virus-
surface spike protein plays a critical role in the cell entry and immune evasion of SARS-CoV …
surface spike protein plays a critical role in the cell entry and immune evasion of SARS-CoV …
From delta to Omicron: S1-RBD/S2 mutation/deletion equilibrium in SARS-CoV-2 defined variants
V Papanikolaou, A Chrysovergis, V Ragos, E Tsiambas… - Gene, 2022 - Elsevier
Abstract Coronavirus-related Severe Acute Respiratory Syndrome (SARS-CoV) in
2002/2003, Middle-East Respiratory Syndrome (MERS-CoV) in 2012/2013, and especially …
2002/2003, Middle-East Respiratory Syndrome (MERS-CoV) in 2012/2013, and especially …