Pharmacological properties and molecular mechanisms of thymol: prospects for its therapeutic potential and pharmaceutical development

MF Nagoor Meeran, H Javed, H Al Taee… - Frontiers in …, 2017 - frontiersin.org
Thymol, chemically known as 2-isopropyl-5-methylphenol is a colorless crystalline
monoterpene phenol. It is one of the most important dietary constituents in thyme species …

Nigella plants–Traditional uses, bioactive phytoconstituents, preclinical and clinical studies

B Salehi, C Quispe, M Imran, I Ul-Haq… - Frontiers in …, 2021 - frontiersin.org
Nigella is a small genus of the family Ranunculaceae, which includes some popular species
due to their culinary and medicinal properties, especially in Eastern Europe, Middle East …

Momordica charantia polysaccharides ameliorate oxidative stress, hyperlipidemia, inflammation, and apoptosis during myocardial infarction by inhibiting the NF-κB …

M Raish - International journal of biological macromolecules, 2017 - Elsevier
The polysaccharide extract of Momordica charantia has various biological activities;
however, its effect on endothelial dysfunction in myocardial infarction remains unclear. To …

Protective effects of α‐bisabolol on altered hemodynamics, lipid peroxidation, and nonenzymatic antioxidants in isoproterenol‐induced myocardial infarction: In vivo …

MFN Meeran, F Laham, H Al‐Taee… - … of biochemical and …, 2018 - Wiley Online Library
The effect of α‐bisabolol on hemodyanimcs, lipid peroxidation, and nonenzymatic
antioxidants was evaluated in isoproterenol‐induced myocardial infarction in rats. They …

Beneficial effects of benfotiamine, a NADPH oxidase inhibitor, in isoproterenol-induced myocardial infarction in rats

LA Ahmed, OF Hassan, O Galal, DF Mansour… - Plos one, 2020 - journals.plos.org
Background Acute myocardial infarction (AMI) remains the most common cause of morbidity
and mortality worldwide. The present study was directed to investigate the beneficial effects …

α-Bisabolol abrogates isoproterenol-induced myocardial infarction by inhibiting mitochondrial dysfunction and intrinsic pathway of apoptosis in rats

MF Nagoor Meeran, F Laham, S Azimullah… - Molecular and cellular …, 2019 - Springer
Mitochondrial dysfunction plays crucial role in the pathologenesis of myocardial infarction
(MI). The present study evaluated the protective effect of α-bisabolol against isoproterenol …

β 肾上腺素能受体在梗死后心脏重构中作用的研究进展

柯樊, 廖梦阳, 邱志华, 廖玉华 - 临床心血管病杂志, 2021 - whuhzzs.com
心肌梗死后心脏重构涉及多种信号传导, 与心力衰竭, 心律失常密切相关. β 肾上腺素能受体(β-
AR) 参与凋亡, 炎症, 纤维化, 心肌肥大等病理过程, 在梗死后心脏重构中发挥关键的调节作用. 3 …

Thymol's modulation of cellular macromolecules, oxidative stress, DNA damage, and NF-kB/caspase-3 signaling in the liver of imidacloprid-exposed rats

FE Abdelgawad, GI Abd El-Rahman, A Behairy… - Environmental …, 2024 - Elsevier
We evaluated whether thymol (THY)(30 mg/kg b. wt) could relieve the adverse effects of the
neonicotinoid insecticide imidacloprid (IMD)(22.5 mg/kg b. wt) on the liver in a 56-day oral …

Inhibitory Effect of Thymol on Tympanostomy Tube Biofilms of Methicillin-Resistant Staphylococcus aureus and Ciprofloxacin-Resistant Pseudomonas aeruginosa

ER Jo, J Oh, SI Cho - Microorganisms, 2022 - mdpi.com
The formation of antibiotic-resistant strain biofilms in tympanostomy tubes results in
persistent and refractory otorrhea. In the present study, we investigated the in vitro …

Blueberry extract attenuates norepinephrine-induced oxidative stress and apoptosis in H9c2 cardiac cells

P Türck, A Nemec-Bakk, T Talwar, Z Suntres… - Molecular and Cellular …, 2022 - Springer
Enhanced sympathetic system activation mediated by norepinephrine (NE) contributes to
adverse cardiac remodeling leading to oxidative stress and cell death, progressing to heart …