Candida albicans is the most common fungal pathogen of humans and has developed an
extensive repertoire of putative virulence mechanisms that allows successful colonization …

The cell wall is essential to nearly every aspect of the biology and pathogenicity of Candida
albicans. Although it was intially considered an almost inert cellular structure that protected …

Highlights•The cell biology of Candida albicans is adapted both for life as a commensal and
as a pathogen.•C. albicans can either downregulate or upregulate virulence properties in …

The Candida albicans cell wall maintains the structural integrity of the organism in addtion to
providing a physical contact interface with the environment. The major components of the …

Metabolism is integral to the pathogenicity of Candida albicans, a major fungal pathogen of
humans. As well as providing the platform for nutrient assimilation and growth in diverse …

Candida albicans is a dimorphic commensal fungus that causes severe oral infections in
immunodeficient patients. Invasion of C. albicans hyphae into oral epithelium is an essential …

Candida albicans is a facultative pathogenic micro‐organism that has developed several
virulence traits enabling invasion of host tissues and avoidance of host defence …

The construction of Candida albicans mutants by targeted gene disruption usually depends
on the use of nutritional markers for the selection of prototrophic transformants from …

Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

Azole antifungal agents, and especially fluconazole, have been used widely to treat
oropharyngeal candidiasis in patients with AIDS. An increasing number of cases of clinical …