Nutraceutical polyphenols: New analytical challenges and opportunities

S Piccolella, G Crescente, L Candela… - Journal of pharmaceutical …, 2019 - Elsevier
Nowadays, the research for secondary metabolites with health promoting effects in
countering or slowing-down chronic and degenerative diseases (eg cancer, cardiovascular …

Antimicrobial capacity of plant polyphenols against gram-positive bacteria: A comprehensive review

FJ Álvarez-Martínez, E Barrajón-Catalán… - Current medicinal …, 2020 - ingentaconnect.com
Background: Multi-drug-resistant bacteria such as Methicillin-Resistant Staphylococcus
aureus (MRSA) disseminate rapidly amongst patients in healthcare facilities and suppose …

Engineering considerations to produce bioactive compounds from plant cell suspension culture in bioreactors

EA Motolinía-Alcántara, CO Castillo-Araiza… - Plants, 2021 - mdpi.com
The large-scale production of plant-derived secondary metabolites (PDSM) in bioreactors to
meet the increasing demand for bioactive compounds for the treatment and prevention of …

Considerations for the use of polyphenols as therapies in neurodegenerative diseases

J Renaud, MG Martinoli - International Journal of Molecular Sciences, 2019 - mdpi.com
Over the last two decades, the increase in the incidence of neurodegenerative diseases due
to the increasingly ageing population has resulted in a major social and economic burden …

Potential therapeutic anti-inflammatory and immunomodulatory effects of dihydroflavones, flavones, and flavonols

C Zaragozá, L Villaescusa, J Monserrat, F Zaragozá… - Molecules, 2020 - mdpi.com
Systemic inflammation, circulating immune cell activation, and endothelial cell damage play
a critical role in vascular pathogenesis. Flavonoids have shown anti-inflammatory effects. In …

Inside and beyond color: Comparative overview of functional quality of tomato and watermelon fruits

R Ilahy, I Tlili, MW Siddiqui, C Hdider… - Frontiers in Plant …, 2019 - frontiersin.org
The quali-quantitative evaluation and the improvement of the levels of plant bioactive
secondary metabolites are increasingly gaining consideration by growers, breeders and …

[HTML][HTML] Binding and antiplatelet activity of quercetin, rutin, diosmetin, and diosmin flavonoids

C Zaragozá, J Monserrat, C Mantecon… - Biomedicine & …, 2021 - Elsevier
Platelets exert an essential role in vascular inflammation and thrombosis. Flavonoids are
natural compounds employed for the clinical management of vascular disorders preventing …

Hibiscus and lemon verbena polyphenols modulate appetite-related biomarkers in overweight subjects: A randomized controlled trial

M Boix-Castejón, M Herranz-López, AP Gago… - Food & function, 2018 - pubs.rsc.org
Trial design: Plant-derived polyphenols have shown potential to alleviate obesity-related
pathologies by a multi-targeted mechanism in animal models and human intervention …

Dietary polyphenols: promising adjuvants for colorectal cancer therapies

L Bracci, A Fabbri, M Del Corno, L Conti - Cancers, 2021 - mdpi.com
Simple Summary Colorectal cancer is a leading cause of death worldwide. Despite the
development of novel surgical and therapeutic strategies, 50% of patients relapse after …

Role of sulphur and heavier chalcogens on the antioxidant power and bioactivity of natural phenolic compounds

ML Alfieri, L Panzella, R Amorati, A Cariola… - Biomolecules, 2022 - mdpi.com
The activity of natural phenols is primarily associated to their antioxidant potential, but is
ultimately expressed in a variety of biological effects. Molecular scaffold manipulation of this …