Quantitative approaches to guide epilepsy surgery from intracranial EEG

JM Bernabei, A Li, AY Revell, RJ Smith… - Brain, 2023 - academic.oup.com
Over the past 10 years, the drive to improve outcomes from epilepsy surgery has stimulated
widespread interest in methods to quantitatively guide epilepsy surgery from intracranial …

Update on the mechanisms and roles of high‐frequency oscillations in seizures and epileptic disorders

P Jiruska, C Alvarado‐Rojas, CA Schevon, R Staba… - …, 2017 - Wiley Online Library
High‐frequency oscillations (HFO s) are a type of brain activity that is recorded from brain
regions capable of generating seizures. Because of the close association of HFO s with …

Virtual cortical resection reveals push-pull network control preceding seizure evolution

AN Khambhati, KA Davis, TH Lucas, B Litt, DS Bassett - Neuron, 2016 - cell.com
In∼ 20 million people with drug-resistant epilepsy, focal seizures originating in
dysfunctional brain networks will often evolve and spread to surrounding tissue, disrupting …

A fingerprint of the epileptogenic zone in human epilepsies

O Grinenko, J Li, JC Mosher, IZ Wang, JC Bulacio… - Brain, 2018 - academic.oup.com
Defining a bio-electrical marker for the brain area responsible for initiating a seizure remains
an unsolved problem. Fast gamma activity has been identified as the most specific marker …

Variability in the location of high frequency oscillations during prolonged intracranial EEG recordings

SV Gliske, ZT Irwin, C Chestek, GL Hegeman… - Nature …, 2018 - nature.com
The rate of interictal high frequency oscillations (HFOs) is a promising biomarker of the
seizure onset zone, though little is known about its consistency over hours to days. Here we …

Estimation of brain network ictogenicity predicts outcome from epilepsy surgery

M Goodfellow, C Rummel, E Abela, MP Richardson… - Scientific reports, 2016 - nature.com
Surgery is a valuable option for pharmacologically intractable epilepsy. However, significant
post-operative improvements are not always attained. This is due in part to our incomplete …

Neuropsychological and neurophysiological aspects of brain‐computer‐interface (BCI) control in paralysis

U Chaudhary, N Mrachacz‐Kersting… - The Journal of …, 2021 - Wiley Online Library
Brain‐computer interfaces (BCIs) aim to help paralysed patients to interact with their
environment by controlling external devices using brain activity, thereby bypassing the …

Low‐voltage fast seizures in humans begin with increased interneuron firing

B Elahian, NE Lado, E Mankin, S Vangala… - Annals of …, 2018 - Wiley Online Library
Objective Intracellular recordings from cells in entorhinal cortex tissue slices show that low‐
voltage fast (LVF) onset seizures are generated by inhibitory events. Here, we determined …

Time-evolving controllability of effective connectivity networks during seizure progression

BH Scheid, A Ashourvan, J Stiso… - Proceedings of the …, 2021 - National Acad Sciences
Over one third of the estimated 3 million people with epilepsy in the United States are
medication resistant. Responsive neurostimulation from chronically implanted electrodes …

Detection of epileptic seizures using phase–amplitude coupling in intracranial electroencephalography

K Edakawa, T Yanagisawa, H Kishima, R Fukuma… - Scientific reports, 2016 - nature.com
Seizure detection using intracranial electroencephalography (iEEG) contributes to improved
treatment of patients with refractory epilepsy. For that purpose, a feature of iEEG to …