Curcumin analogues and their hybrid molecules as multifunctional drugs
SA Noureddin, RM El-Shishtawy, KO Al-Footy - European journal of …, 2019 - Elsevier
Abstract Curcumin (diferuloylmethane or 1, 7-bis (4-hydroxy-3-methoxyphenyl)-1, 6-
heptadiene-3, 5-dione) is an interesting compound that is characterized by a special …
heptadiene-3, 5-dione) is an interesting compound that is characterized by a special …
Curcumin analogues and derivatives with anti-proliferative and anti-inflammatory activity: Structural characteristics and molecular targets
E Chainoglou, D Hadjipavlou-Litina - Expert opinion on drug …, 2019 - Taylor & Francis
ABSTRACT Introduction: Curcumin (Diferuloylmethane) is a natural phenolic compound,
which belongs to the curcuminoid family, presenting pleiotropic activity and low …
which belongs to the curcuminoid family, presenting pleiotropic activity and low …
Synthesis, structural, and intriguing electronic properties of symmetrical bis-aryl-α, β-unsaturated ketone derivatives
Three symmetrical bis-aryl-α, β-unsaturated ketone derivatives, 2, 6-di ((E)-benzylidene)-
cyclohexan-1-one (DBC), 2, 6-bis ((E)-4-chlorobenzylidene) cyclohexan-1-one (BCC), and …
cyclohexan-1-one (DBC), 2, 6-bis ((E)-4-chlorobenzylidene) cyclohexan-1-one (BCC), and …
Acid catalyzed one-pot approach towards the synthesis of curcuminoid systems: unsymmetrical diarylidene cycloalkanones, exploration of their single crystals, optical …
In the present study crystalline unsymmetrical diarylidene ketone derivatives BNTP and
BDBC have been prepared by two sequential acid catalyzed aldol condensation reactions in …
BDBC have been prepared by two sequential acid catalyzed aldol condensation reactions in …
Facile preparation, characterization, SC-XRD and DFT/DTDFT study of diversely functionalized unsymmetrical bis-aryl-α, β-unsaturated ketone derivatives
The current research work is about the synthesis of diversely functionalized unsymmetrical
mono-carbonyl curcuminoids:(1E, 4E)-1-(2-methoxy-4-nitrophenyl)-5-(4-methoxyphenyl)-2 …
mono-carbonyl curcuminoids:(1E, 4E)-1-(2-methoxy-4-nitrophenyl)-5-(4-methoxyphenyl)-2 …
An overview of structure–activity relationship studies of curcumin analogs as antioxidant and anti-inflammatory agents
Curcumin, extracted mainly from Curcuma longa rhizomes, has been reported to possess
potent anti-inflammatory and anti-oxidant activities. Although safe at higher doses and …
potent anti-inflammatory and anti-oxidant activities. Although safe at higher doses and …
Mesalazine/hydroxypropyl-β-cyclodextrin/chitosan nanoparticles with sustained release and enhanced anti-inflammation activity
P Tang, Q Sun, L Zhao, H Pu, H Yang, S Zhang… - Carbohydrate …, 2018 - Elsevier
This study aimed to develop a novel sustained release system for mesalazine (MSZ) by
preparing hydroxypropyl-β-cyclodextrin (HP-β-CD) inclusion complex loaded chitosan (CS) …
preparing hydroxypropyl-β-cyclodextrin (HP-β-CD) inclusion complex loaded chitosan (CS) …
Immunosuppressive effects of natural α, β-unsaturated carbonyl-based compounds, and their analogs and derivatives, on immune cells: a review
The immune system is complex and pervasive as it functions to prevent or limit infections in
the human body. In a healthy organism, the immune system and the redox balance of …
the human body. In a healthy organism, the immune system and the redox balance of …
Insights on the synthesis of asymmetric curcumin derivatives and their biological activities
Curcumin is a small organic molecule with pleiotropic biological activities. However, its
multiple structural-pharmacokinetic challenges prevent its development into a clinical drug …
multiple structural-pharmacokinetic challenges prevent its development into a clinical drug …
Anti-infammatory scalemic chromanoids and chromenoids from Rhododendron dauricum
N Zhang, LL Xiong, DJ Sun, M Zhu, ZY Zhao, H Li… - Fitoterapia, 2022 - Elsevier
Four pairs of undescribed chromane and chromene meroterpenoid scalemic mixtures (1a/1b-
4a/4b), together with three pairs of known chromane meroterpenoid ones (5a/5b-7a/7b) …
4a/4b), together with three pairs of known chromane meroterpenoid ones (5a/5b-7a/7b) …