Frameworks for targeting RNA with small molecules
AU Juru, AE Hargrove - Journal of Biological Chemistry, 2021 - ASBMB
Since the characterization of mRNA in 1961, our understanding of the roles of RNA
molecules has significantly grown. Beyond serving as a link between DNA and proteins …
molecules has significantly grown. Beyond serving as a link between DNA and proteins …
Ribosome‐targeting antibacterial agents: Advances, challenges, and opportunities
L Zhang, J He, L Bai, S Ruan, T Yang… - Medicinal Research …, 2021 - Wiley Online Library
Ribosomes, which synthesize proteins, are critical organelles for the survival and growth of
bacteria. About 60% of approved antibiotics discovered so far combat pathogenic bacteria …
bacteria. About 60% of approved antibiotics discovered so far combat pathogenic bacteria …
Small molecule–RNA targeting: starting with the fundamentals
AE Hargrove - Chemical Communications, 2020 - pubs.rsc.org
The structural and regulatory elements in therapeutically relevant RNAs offer many
opportunities for targeting by small molecules, yet fundamental understanding of what drives …
opportunities for targeting by small molecules, yet fundamental understanding of what drives …
[HTML][HTML] Copper nanoclusters modified molybdenum disulfide quantum dots probe for sensitive detection of tetracycline
X Tang, H Chi, Z Jia, J Lv, Y Lv, J Wu - Sensing and Bio-Sensing Research, 2024 - Elsevier
By combining molybdenum disulfide quantum dots (MoS 2 QDs) synthesized using a facile
hydrothermal method with copper nanoclusters (Cu NCs), copper-ion-modified molybdenum …
hydrothermal method with copper nanoclusters (Cu NCs), copper-ion-modified molybdenum …
Copper Ion Modified Molybdenum Disulfide Probe for Sensitive Detection of Tetracycline
X Tang, H Chi, Z Jia, J Lv, Y Lv - Available at SSRN 4633133 - papers.ssrn.com
The molybdenum disulfide probe synthesized by a one-step hydrothermal method was
mixed with copper nanoclusters to obtain a copper ion modified molybdenum disulfide …
mixed with copper nanoclusters to obtain a copper ion modified molybdenum disulfide …
RNA-Targeted Small Molecule Ligand Discovery via Imine-Based Dynamic Combinatorial Chemistry
AU Juru - 2021 - search.proquest.com
In addition to coding for proteins, RNA molecules play direct functional roles in cellular
metabolism, including the regulation of chromatin architecture and the regulation of gene …
metabolism, including the regulation of chromatin architecture and the regulation of gene …