A historical perspective on estradiol's enhancement of cognitive function is presented, and
research, primarily in animals, but also in humans, is reviewed. Data regarding the …

There is ample empirical evidence to support the notion that the biological impacts of
estrogen extend beyond the gonads to other bodily systems, including the brain and …

This article is part of a Special Issue “Estradiol and Cognition”. There are sex differences in
hippocampus-dependent cognition and neurogenesis suggesting that sex hormones are …

The hippocampus is an area of the brain that undergoes dramatic plasticity in response to
experience and hormone exposure. The hippocampus retains the ability to produce new …

A promising strategy to delay and perhaps prevent Alzheimer's disease (AD) is to identify the
age-related changes that put the brain at risk for the disease. A significant normal age …

This review presents evidence for the idea that the expression of estrogen receptor alpha
and beta (ERα and ERβ) interacts with the level of estradiol (E2) to influence the etiology of …

The pros and cons of estrogen therapy for use in postmenopausal women continue to be a
major topic of debate in women's health. Much of this debate focuses on the potential …

The ovarian hormones 17β-estradiol (E 2) and progesterone (P 4) are potent modulators of
hippocampal memory formation. Both hormones have been demonstrated to enhance …

This article is part of a Special Issue" Hormones & Neurotrauma". Estrogens have been
shown to be protective agents against neurodegeneration and associated cognitive decline …

This article is part of a Special Issue" Hormones & Neurotrauma". Epilepsy is the third most
common chronic neurological disorder. Clinical and experimental evidence supports the …