Recent advances in developing polymeric micelles for treating cancer: Breakthroughs and bottlenecks in their clinical translation

J Kaur, M Gulati, NK Jha, J Disouza, V Patravale… - Drug Discovery …, 2022 - Elsevier
Polymeric micelles (PMs) have been explored pre-clinically for the delivery of
chemotherapeutics to treat cancer. Their unique features, such as easy surface …

Boron Vehiculating Nanosystems for Neutron Capture Therapy in Cancer Treatment

G Ailuno, A Balboni, G Caviglioli, F Lai, F Barbieri… - Cells, 2022 - mdpi.com
Boron neutron capture therapy is a low-invasive cancer therapy based on the neutron fission
process that occurs upon thermal neutron irradiation of 10B-containing compounds; this …

(Bio) degradable and biocompatible Nano-objects from polymerization-induced and crystallization-driven self-assembly

C Zhu, J Nicolas - Biomacromolecules, 2022 - ACS Publications
Polymerization-induced self-assembly (PISA) and crystallization-driven self-assembly
(CDSA) techniques have emerged as powerful approaches to produce a broad range of …

Polymers and boron neutron capture therapy (BNCT): A potent combination

A Pitto-Barry - Polymer Chemistry, 2021 - pubs.rsc.org
Boron neutron capture therapy (BNCT) has a long history of unfulfilled promises for the
treatment of aggressive cancers. In the last two decades, chemists, physicists, and clinical …

Polymerization‐induced self‐assembly for drug delivery: A critical appraisal

EG Hochreiner… - Journal of Polymer …, 2023 - Wiley Online Library
Polymerization‐induced self‐assembly (PISA) with (in situ) encapsulation of (therapeutic)
cargo has proven to be an efficient preparation method for loaded polymeric micelles and …

[HTML][HTML] Tailored hyaluronic acid-based nanogels as theranostic boron delivery systems for boron neutron cancer therapy

S Coninx, G Kalot, A Godard, E Bodio, C Goze… - International Journal of …, 2022 - Elsevier
Boron-rich nanocarriers possess great potential for advanced boron neutron capture therapy
(BNCT) as an effective radiation treatment for invasive malignant tumors. If additionally, they …

Stabilizing Entropically Driven Self-Assembly of Self-Immolative Polyurethanes in Water: A Strategy for Tunable Encapsulation Stability and Controlled Cargo Release

S Santra, A Ghosh, A Mondal, SM Ali… - ACS Applied Polymer …, 2022 - ACS Publications
Stimuli-responsive amphiphilic polymer assemblies are of great interest in the area of
targeted drug delivery applications as they can sequester guest molecules in one set of …

Polymerization-induced self-assembly of (2-(4-vinylbenzyl) iso-indoline-1, 3-dione) for the synthesis of hydrazine responsive block copolymer nanoparticles

SR Mane, AS Carlini - Polymer Chemistry, 2024 - pubs.rsc.org
Well-defined core–shell nanoparticles with a phthalimide core are synthesized using
reversible addition–fragmentation chain transfer (RAFT)-mediated dispersion polymerization …

Extracellular Vesicles Comprising Carborane Prepared by a Host Exchanging Reaction as a Boron Carrier for Boron Neutron Capture Therapy

R Kawasaki, A Oshige, N Kono, K Yamana… - … Applied Materials & …, 2024 - ACS Publications
With their low immunogenicity and excellent deliverability, extracellular vesicles (EVs) are
promising platforms for drug delivery systems. In this study, hydrophobic molecule loading …

Modulating living crystallization-driven self-assembly behaviors of oligo (p-phenylene ethynylene)-containing block copolymers and micellar stability by solvent and …

J Nie, L Xia, X Huang, G Lu, C Feng - Polymer Chemistry, 2023 - pubs.rsc.org
Living crystallization-driven self-assembly with separated nucleation and growth stages
enables the formation of uniform fiber-like micelles with precise length/composition. The …