Cobalt Protoporphyrin blocks EqHV-8 infection via IFN-α/β production

L Li, X Hu, S Li, Y Li, S Zhao, F Shen, C Wang, Y Li… - Animals, 2023 - mdpi.com
Simple Summary Equid alphaherpesvirus type 8 (EqHV-8) infection presents equids with
severe respiratory disease, abortions, and neurological syndromes. No vaccines and …

The emergence of viral encephalitis in donkeys by equid herpesvirus 8 in China

T Wang, L Hu, M Liu, T Wang, X Hu, Y Li… - Frontiers in …, 2022 - frontiersin.org
The equine herpesvirus type 8 (EHV-8) can cause significant economic losses in the global
horses and donkey industry. The disease has been associated with abortion and respiratory …

[HTML][HTML] Protective role of cepharanthine against equid herpesvirus type 8 through AMPK and Nrf2/HO-1 pathway activation

S Li, L Li, Y Sun, MZ Khan, Y Yu, L Ruan, L Chen… - Viruses, 2024 - mdpi.com
Equid herpesvirus type 8 (EqHV-8) is known to cause respiratory disease and miscarriage in
horses and donkeys, which is a major problem for the equine farming industry. However …

Characteristics and epidemiological investigation of equid herpesvirus 8 in donkeys in Shandong, China

T Wang, C Xi, Y Yu, W Liu, MF Akhtar, Y Li, C Wang… - Archives of …, 2023 - Springer
Abstract Equid herpesvirus 8 (EHV-8), also known as asinine herpesvirus type 3 (AHV-3),
can cause severe respiratory disease, abortion in mares, and neurological disorders. There …

Heme oxygenase-1 is an equid alphaherpesvirus 8 replication restriction host protein and suppresses viral replication via the PKCβ/ERK1/ERK2 and NO/cGMP/PKG …

T Wang, S Li, X Hu, Y Geng, L Chen, W Liu… - Microbiology …, 2024 - Am Soc Microbiol
ABSTRACT Equid alphaherpesvirus 8 (EqHV-8) is one of the most economically important
viruses that is known to cause severe respiratory disease, abortion, and neurological …

Characterizing the pathogenesis and immune response of equine herpesvirus 8 infection in lung of mice

L Hu, T Wang, H Ren, W Liu, Y Li, C Wang, L Li - Animals, 2022 - mdpi.com
Simple Summary Equine herpesvirus 8 (EHV-8) is an important pathogen primarily affecting
the horse and donkey industry, but there is little information about the pathogenicity and …

Pathogenicity and host cytokines response of EqHV-8 infection in C57BL/6J mice

S Li, C Xi, Y Geng, W Tian, L Li, T Wang, J Zhao - Microbial Pathogenesis, 2024 - Elsevier
Abstract Equid herpesvirus type 8 (EqHV-8) is known to cause abortion, respiratory signs,
and viral encephalitis in equines. EqHV-8 has been reported to cause serious economic …

Rutin prevents EqHV-8 induced infection and oxidative stress via Nrf2/HO-1 signaling pathway

L Chen, S Li, W Li, Y Yu, Q Sun, W Chen… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction The Nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1)
signaling pathway has been extensively studied for its role in regulating antioxidant and …

Identification of equine herpesvirus 8 in donkey abortion: a case report

T Wang, L Hu, Y Wang, W Liu, G Liu, M Zhu, W Zhang… - Virology journal, 2022 - Springer
Abstract Background Equine herpesvirus-8 (EHV-8) is one of the most economically
significant viruses that infect mammals of the genus Equus worldwide, which cause severe …

Identification of asinine gamma herpesviruses in a donkey with interstitial pulmonary fibrosis, pleural effusion and thrombocytopenia

I Imposimato, LV Muscatello, N Ellero, D Lelli… - Journal of Equine …, 2024 - Elsevier
A 23-year-old domestic donkey (Equus asinus) referred for severe respiratory distress due to
suspected equine asthma. Ultrasound of the chest revealed bilateral irregular pulmonary …