Multiple functions of p27 in cell cycle, apoptosis, epigenetic modification and transcriptional regulation for the control of cell growth: A double-edged sword protein

M Abbastabar, M Kheyrollah, K Azizian, N Bagherlou… - DNA repair, 2018 - Elsevier
The cell cycle is controlled by precise mechanisms to prevent malignancies such as cancer,
and the cell needs these tight and advanced controls. Cyclin dependent kinase inhibitor p27 …

Fermented soy products and their potential health benefits: A review

FG do Prado, MGB Pagnoncelli, GV de Melo Pereira… - Microorganisms, 2022 - mdpi.com
In the growing search for therapeutic strategies, there is an interest in foods containing
natural antioxidants and other bioactive compounds capable of preventing or reversing …

LncRNA2Target v2. 0: a comprehensive database for target genes of lncRNAs in human and mouse

L Cheng, P Wang, R Tian, S Wang, Q Guo… - Nucleic acids …, 2019 - academic.oup.com
Long non-coding RNAs (lncRNAs) play crucial roles in regulating gene expression, and a
growing number of researchers have focused on the identification of target genes of …

Cancer-associated Fibroblast–promoted LncRNA DNM3OS Confers Radioresistance by Regulating DNA Damage Response in Esophageal Squamous Cell …

H Zhang, Y Hua, Z Jiang, J Yue, M Shi, X Zhen… - Clinical Cancer …, 2019 - AACR
Purpose: Our study aimed to investigate whether CAF (cancer-associated fibroblasts) were
involved in long noncoding RNAs (lncRNA)-regulated radioresponse in esophageal …

53BP1: A key player of DNA damage response with critical functions in cancer

M Mirza-Aghazadeh-Attari, A Mohammadzadeh… - DNA repair, 2019 - Elsevier
Maintenance of genome integrity and stability is a critical responsibility of the DNA damage
response (DDR) within cells, such that any disruption in this kinase-based signaling …

lncRNA ZFAS1 improves neuronal injury and inhibits inflammation, oxidative stress, and apoptosis by sponging miR-582 and upregulating NOS3 expression in …

Y Zhang, Y Zhang - Inflammation, 2020 - Springer
The interplay between lncRNAs and miRNAs was reported to be associated with cerebral
ischemia reperfusion injury (CIRI). Besides, the lncRNA ZFAS1 was significantly …

The impact of lncRNA dysregulation on clinicopathology and survival of breast cancer: a systematic review and meta-analysis

T Tian, M Wang, S Lin, Y Guo, Z Dai, K Liu… - … Therapy-Nucleic Acids, 2018 - cell.com
Dysregulation of multiple long non-coding RNAs (lncRNAs) was reported to play major roles
in breast cancer (BC). Here we aimed to collect most of the relevant literature to assess the …

Targeting oxidatively induced DNA damage response in cancer: opportunities for novel cancer therapies

P Davalli, G Marverti, A Lauriola… - Oxidative medicine and …, 2018 - Wiley Online Library
Cancer is a death cause in economically developed countries that results growing also in
developing countries. Improved outcome through targeted interventions faces the scarce …

MiRNAs and inflammatory bowel disease: An interesting new story

S Moein, M Vaghari‐Tabari, D Qujeq… - Journal of Cellular …, 2019 - Wiley Online Library
Inflammatory bowel disease (IBD), as a chronic and recurrent inflammatory disorder, is
caused by a dysregulated and aberrant immune response to exposed environmental factors …

Crosstalk between Phosphoinositide 3‐kinase/Akt signaling pathway with DNA damage response and oxidative stress in cancer

A Karimian, SM Mir, H Parsian… - Journal of cellular …, 2019 - Wiley Online Library
Abstract The phosphatidylinositol 3‐kinases (PI3K)/Akt signaling pathway is one of the well‐
characterized and most important signaling pathways activated in response to DNA …