Estrogen receptor alpha (ERα), a nuclear transcription factor, is a well-validated therapeutic
target for more than 70% of all breast cancers (BCs). Antagonizing ERα either by selective …

Benign prostatic hyperplasia (BPH) and prostatic cancer are aging-associated urological
conditions in men. While significant advances have been made in relation to treatment, poor …

The current study's objective was to investigate how an antifungal pesticide Azoxystrobin
(AZO) interacts with bovine serum albumin (BSA) under conditions that simulate a …

The synthesis of sulfonamide-functionalized magnetic porous nanocomposites is highly
significant in chemistry due to their exceptional properties and potential as catalysts. COFs …

Compounds containing 1, 2, 4-triazoles and hydrazone structural frameworks have been
widely studied and demonstrated to exhibit a wide range of pharmacological properties. In …

Acute myeloid leukemia (AML) is one of the cancers that grow most aggressively. The
challenges in AML management are huge, despite many treatment options. Mutations in …

Indole heterocycles have been considered as noteworthy associated hybrids because of
their diverse applications in organic synthesis, and coordination chemistry, as well as in the …

A benign approach to valuable 3-aryl-indolin-2-ones was developed based on palladium
(II)/Lewis acid-cocatalyzed cyclocarbonylation of readily available (2-aminoaryl)(aryl) …

In recent years, a cancer research trend has shifted towards identifying novel therapeutic
compounds from natural assets for the management of cancer. In this study, we aimed to …

The production of tomato products is massive in Italy resulting in a huge amount of tomato
waste as seeds, peels and stems. The aim of our work is to re-utilize these matrices through …