Tuberculosis (TB) is the leading infectious cause of mortality worldwide, due in part to a
limited understanding of its clinical pathogenic spectrum of infection and disease …

The causative agent of human tuberculosis, Mycobacterium tuberculosis complex (MTBC),
comprises seven phylogenetically distinct lineages associated with different geographical …

Tuberculosis (TB) remains a leading cause of death globally. Dissemination of TB to the
brain results in the most severe form of extrapulmonary TB, tuberculous meningitis (TBM) …

Strains of the Beijing/W genotype family of Mycobacterium tuberculosis have caused large
outbreaks of tuberculosis, sometimes involving multidrug resistance. This genetically highly …

The wide geographic distribution of one clade of Mycobacterium tuberculosis, the Beijing
genotype family, and its genetic homogeneity, suggests that strains belonging to this …

In the last decade, an unprecedented genetic diversity has been disclosed among
Mycobacterium tuberculosis strains found worldwide. However, well-conserved genotypes …

Molecular epidemiologic studies of tuberculosis (TB) have focused largely on utilizing
molecular techniques to address short-and long-term epidemiologic questions, such as in …

A large, genetically related group of Mycobacterium tuberculosis strains, variously called W
or Beijing, is distinguished by specific molecular markers and referred to as the W-Beijing …

Multidrug-resistant tuberculosis (MDR) is perceived as a growing hazard to human health
worldwide. Judgments about the true scale of the problem, and strategies for containing it …

The Beijing family is the most successful genotype of Mycobacterium tuberculosis and
responsible for more than a quarter of the global tuberculosis epidemic. As the predominant …