Objectives This review proposes case definitions and diagnostic considerations of systemic
disorders and conditions that affect the periodontal attachment apparatus. Importance …

The human body is colonized by abundant and diverse microorganisms, collectively known
as the microbiome. The oral cavity has more than 700 species of bacteria and consists of …

Background Recent achievement in genetics and epigenetics has led to the exploration of
the pathogenesis of systemic lupus erythematosus (SLE). Identification of differentially …

Osteoporosis (OP) is a highly prevalent orthopedic condition in postmenopausal women and
the elderly. Currently, OP treatments mainly include bisphosphonates, receptor activator of …

Background Systemic lupus erythematosus (SLE) is a chronic systemic inflammatory
autoimmune disease, the etiology of which remains only partially characterized. Strong …

Cell signaling pathways regulate much in the life of a cell: from shuttling cargo through
intracellular compartments and onto the cell surface, how it should respond to stress …

Systemic lupus erythematosus (SLE) is a serious autoimmune disease with variety of organ
manifestations. The most dreadful one, affecting the majority of SLE patients, is kidney …

Abstract Both Systemic Lupus Erythematosus (SLE) and periodontal disease (PD) present a
similar immunological profile mainly characterized by altered cytokine levels. In this study …

Complex disease is a cascade process which is associated with functional abnormalities in
multiple proteins and protein-protein interaction (PPI) networks. One drug one target has not …

Background Previous observational studies have shown a bidirectional association between
immune-mediated inflammatory disorders (IMID) and periodontal disease. However …