Transcriptional regulation is a fundamental molecular mechanism involved in almost every
aspect of life, from homeostasis to development, from metabolism to behavior, from reaction …

Proteins are central to all of the processes of life. For their activity, they almost invariably
need to interact with other macromolecules, be they nucleic acids, membranes, glycans, or …

Abstract ATTED-II (https://atted. jp) is a gene coexpression database for nine plant species
based on publicly available RNAseq and microarray data. One of the challenges in …

Qingfei Paidu decoction (QFPD), a multi-component herbal formula, has been widely used
to treat COVID-19 in China. However, its active compounds and mechanisms of action are …

Background Co-expression correlations provide the ability to predict gene functionality
within specific biological contexts, such as different tissue and disease conditions. However …

Gene co-expression analysis has emerged as a powerful method to provide insights into
gene function and regulation. The rapid growth of publicly available RNA-sequencing (RNA …

Numerous experimental studies have indicated that alteration and dysregulation in
mircroRNAs (miRNAs) are associated with serious diseases. Identifying disease-related …

RNA is modified by hundreds of chemical reactions and folds into innumerable shapes.
However, the regulatory role of RNA sequence and structure and how dysregulation leads to …

Gene coexpression is synchronization of gene expression across many cellular and
environmental conditions and is widely used to infer the biological function of genes. Gene …

Parkinson's disease (PD) is a complex neurodegenerative disorder without a cure. The
onset of PD symptoms corresponds to 50% loss of midbrain dopaminergic (mDA) neurons …