Triple-negative breast cancer (TNBC), a subtype of breast cancer, is defined as lacking
estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor …

Assessment of tumor-infiltrating lymphocytes (TILs) in histopathologic specimens can
provide important prognostic information in diverse solid tumor types, and may also be of …

Background The objective of this systematic review and meta-analysis was to determine the
prognostic value of total tumor-infiltrating lymphocytes (TILs) and subtypes of TILs (CD4+ …

Tumors develop multiple mechanisms of immune evasion as they progress, with some
cancer types being inherently better at 'hiding'than others. With an increased understanding …

Immune checkpoint blockade has been a pivotal development in the management of
advanced non–small-cell lung cancer (NSCLC). Although durable antitumour activity and …

Triple-negative breast cancer (TNBC) is a special subtype of breast cancer, accounting for
10–20% of breast cancers with high intrinsic heterogeneity. Its unique immune …

Chemokine CXC motif ligand 13 (CXCL13), originally identified as a B-cell chemokine, plays
an important role in the immune system. The interaction between CXCL13 and its receptor …

Purpose Tumor inflammatory response was evaluated as a prognostic feature in triple-
negative breast cancer (TNBC) and compared with the clinical prognosticators of breast …

Abstract The American Joint Committee on Cancer/Union Internationale Contre le Cancer
(AJCC/UICC) tumor, nodes, metastasis (TNM) classification system based on tumor features …

Simple Summary The assessment of tumor-infiltrating lymphocytes (TILs) is gaining
acceptance as a robust biomarker to help predict prognosis and treatment response. We …