Functional cognitive disorders: a systematic review

L McWhirter, C Ritchie, J Stone, A Carson - The Lancet Psychiatry, 2020 - thelancet.com
Cognitive symptoms are common, and yet many who seek help for cognitive symptoms
neither have, nor go on to develop, dementia. A proportion of these people are likely to have …

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the …

P Lewczuk, P Riederer, SE O'bryant… - The world journal of …, 2018 - Taylor & Francis
In the 12 years since the publication of the first Consensus Paper of the WFSBP on
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …

Predicting progression to dementia in persons with mild cognitive impairment using cerebrospinal fluid markers

RLH Handels, SJB Vos, MG Kramberger, V Jelic… - Alzheimer's & …, 2017 - Elsevier
Introduction We aimed to determine the added value of cerebrospinal fluid (CSF) to clinical
and imaging tests to predict progression from mild cognitive impairment (MCI) to any type of …

Cost-utility of using Alzheimer's disease biomarkers in cerebrospinal fluid to predict progression from mild cognitive impairment to dementia

RLH Handels, A Wimo, R Dodel… - Journal of …, 2017 - content.iospress.com
Background: Diagnostic research criteria for Alzheimer's disease support the use of
biomarkers in the cerebrospinal fluid (CSF) to improve the accuracy of the prognosis …

Optimising Alzheimer's disease diagnosis and treatment: assessing cost-utility of integrating blood biomarkers in clinical practice for disease-modifying treatment

S Aye, R Handels, B Winblad, L Jönsson - The Journal of Prevention of …, 2024 - Springer
Background Recent developments in blood biomarkers (BBM) have shown promising
results in diagnosing amyloid pathology in Alzheimer's Disease (AD). However, information …

I think, therefore I forget–using experimental simulation of dementia to understand functional cognitive disorders

L McWhirter, B Sargent, C Ritchie, J Stone… - CNS spectrums, 2020 - cambridge.org
Background. Symptoms of functional neurological disorder have traditionally been thought
to depend, in part, on patients' ideas about symptoms rather than on the rules of …

Cerebrospinal fluid markers of extracellular matrix remodelling, synaptic plasticity and neuroinflammation before and after cranial radiotherapy

E Fernström, K Minta, U Andreasson… - Journal of internal …, 2018 - Wiley Online Library
Background Advances in the treatment of brain tumours have increased the number of long‐
term survivors, but at the cost of side effects following cranial radiotherapy ranging from …

[HTML][HTML] Functional cognitive disorder: beyond pseudodementia.

DS Marín-Medina, PA Arenas-Vargas… - Neurology …, 2024 - Elsevier
Introduction Many patients with cognitive symptoms, such as subjective memory complaints,
may in fact have functional cognitive disorder. Development This review explores various …

The development of biomarkers to reduce attrition rate in drug discovery focused on oncology and central nervous system

M Safavi, R Sabourian, M Abdollahi - Expert Opinion on Drug …, 2016 - Taylor & Francis
Introduction: The task of discovery and development of novel therapeutic agents remains an
expensive, uncertain, time-consuming, competitive, and inefficient enterprise. Due to a …

Added diagnostic accuracy after [18F] flutemetamol PET scanning in young patients with dementia in an academic memory clinic setting

RLH Handels, MD Zwan, W Pelkmans, GJ Biessels… - medRxiv, 2021 - medrxiv.org
Introduction A timely diagnosis of Alzheimer's Disease (AD) in an early stage of dementia is
important to support timely access to treatment, advice, and care. The aim of this study was …